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Zhengrong Guan
Assistant Professor
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zrguan@uab.edu
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Zhengrong Guan
Assistant Professor
Positions
Associate Scientist (C)
,
Center for Clinical and Translational Science (CCTS)
,
General Clinical Research Center
Associate Scientist (C)
,
Nephrology Research & Training Center
,
General Clinical Research Center
Assistant Professor (P)
,
Medicine - Nephrology
,
Department of Medicine
Assistant Professor (S)
,
Cell, Developmental and Integrative Biology (CDIB)
,
Academic Joint Departments
Publications
Research
Background
Contact
Publications
Selected Publications
Academic Article
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Year
Title
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2022
Sex Difference in Autoregulatory Responses of Juxtamedullary Afferent Arterioles Following Ischemia-Reperfusion in Rats
2022
2022
Editorial: Hypertension and Chronic Kidney Injury or Failure, Volume II
.
Frontiers in Physiology
. 12.
2022
2021
Editorial: Hypertension and Chronic Kidney Injury or Failure
.
Frontiers in Physiology
. 12.
2021
2021
Restoration of afferent arteriolar autoregulatory behavior in ischemia-reperfusion injury in rat kidneys
2021
2020
Avian erythroblastosis virus E26 oncogene homolog-1 (ETS-1) plays a role in renal microvascular pathophysiology in the Dahl salt-sensitive rat
.
Kidney International
. 97:528-537.
2020
2020
Purinoceptors, renal microvascular function and hypertension
.
Physiological Research
. 69:353-369.
2020
2019
Rho kinase inhibitors reduce voltage-dependent Ca
2+
channel signaling in aortic and renal microvascular smooth muscle cells
2019
2018
Mechanisms of sphingosine-1-phosphate-mediated vasoconstriction of rat afferent arterioles
.
Acta Physiologica
. 222.
2018
2016
Pentosan polysulfate preserves renal microvascular P2X
1
receptor reactivity and autoregulatory behavior in DOCA-salt hypertensive rats
2016
2016
Metabolism of
13
C
5
-hydroxyproline in mouse models of Primary Hyperoxaluria and its inhibition by RNAi therapeutics targeting liver glycolate oxidase and hydroxyproline dehydrogenase
2016
2015
Endothelin and the Renal Microcirculation
.
Seminars in Nephrology
. 35:145-155.
2015
2015
Endothelin contributes to blunted renal autoregulation observed with a high-salt diet
2015
2014
Sphingosine-1-phosphate evokes unique segment-specific vasoconstriction of the renal microvasculature
.
Journal of the American Society of Nephrology
. 25:1774-1785.
2014
2014
P2 receptors in renal autoregulation
2014
2013
Immunosuppression preserves renal autoregulatory function and microvascular P2X
1
receptor reactivity in ANG II-hypertensive rats
2013
2011
Endothelin and the renal vasculature.
.
Contributions to Nephrology
. 172:35-49.
2011
2011
Endothelin and the renal vasculature
.
Contributions to Nephrology
. 172:35-49.
2011
2011
Role of adenosine 5′-triphosphate in regulating renal microvascular function and in hypertension
.
Hypertension
. 58:333-340.
2011
2011
P2X
1
receptor-mediated vasoconstriction of afferent arterioles in angiotensin II-infused hypertensive rats fed a high-salt diet
.
Hypertension
. 57:780-787.
2011
2010
Response to role of epithelial sodium channels in the renal myogenic response?
.
Hypertension
. 55.
2010
2010
Pentosan polysulfate treatment preserves renal autoregulation in ANG II-infused hypertensive rats via normalization of P2X
1
receptor activation
2010
2009
Effect of epithelial sodium channel blockade on the myogenic response of rat juxtamedullary afferent arterioles
.
Hypertension
. 54:1062-1069.
2009
2007
P2X receptors as regulators of the renal microvasculature
.
Trends in Pharmacological Sciences
. 28:646-652.
2007
2007
Purinoceptors in the kidney
.
Experimental Biology and Medicine
. 232:715-726.
2007
2006
Delayed administration of darbepoetin or erythropoietin protects against ischemic acute renal injury and failure
.
Kidney International
. 69:1806-1813.
2006
2006
Renal endothelial dysfunction and impaired autoregulation after ischemia-reperfusion injury result from excess nitric oxide
2006
2004
Angiotensin II facilitates autoregulation in the perfused mouse kidney: An optimized in vitro model for assessment of renal vascular and tubular function
.
Nephrology
. 9:288-296.
2004
2003
Facilitation of renal autoregulation by angiotensin II is mediated through modulation of nitric oxide
.
Acta Physiologica
. 179:189-201.
2003
Research
Principal Investigator On
Sphingosine-1-Phosphate in Ischemia-Reperfusion Induced Renal Microvascular Injury
awarded by
American Heart Association (Southeast Affiliate)
Sphingosine-1-Phosphate in Renal Microvascular Dysfunction of Ischemia-Reperfusion Kidney Injury
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
Investigator On
Glycolate Metabolism and Kidney Oxalate
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
Interdisciplinary Training In Kidney-Related Research
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
Interdisciplinary Training in Kidney-Related Research
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
Kidney Undergraduate Research Experience (KURE)
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
PRedOctoral Phd and MD Research Training In TEams (PROmoTE)
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
PRedoctoral Interdisciplinary Training in Renal Physiology and MEdIcIne (PRIME)
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
TLR4 in the Regulation of Renal Microvascular Function
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
Background
Education And Training
Doctor of Philosophy in Medical Scientist,
2004
Contact
Full Name
Zhengrong
Guan