Positions

Selected Publications

Academic Article

Year Title Altmetric
2022 Sex Difference in Autoregulatory Responses of Juxtamedullary Afferent Arterioles Following Ischemia-Reperfusion in Rats 2022
2022 Editorial: Hypertension and Chronic Kidney Injury or Failure, Volume IIFrontiers in Physiology.  12. 2022
2021 Editorial: Hypertension and Chronic Kidney Injury or FailureFrontiers in Physiology.  12. 2021
2021 Restoration of afferent arteriolar autoregulatory behavior in ischemia-reperfusion injury in rat kidneys 2021
2020 Avian erythroblastosis virus E26 oncogene homolog-1 (ETS-1) plays a role in renal microvascular pathophysiology in the Dahl salt-sensitive ratKidney International.  97:528-537. 2020
2020 Purinoceptors, renal microvascular function and hypertensionPhysiological Research.  69:353-369. 2020
2019 Rho kinase inhibitors reduce voltage-dependent Ca2+ channel signaling in aortic and renal microvascular smooth muscle cells 2019
2018 Mechanisms of sphingosine-1-phosphate-mediated vasoconstriction of rat afferent arteriolesActa Physiologica.  222. 2018
2016 Pentosan polysulfate preserves renal microvascular P2X1 receptor reactivity and autoregulatory behavior in DOCA-salt hypertensive rats 2016
2016 Metabolism of 13C5-hydroxyproline in mouse models of Primary Hyperoxaluria and its inhibition by RNAi therapeutics targeting liver glycolate oxidase and hydroxyproline dehydrogenase 2016
2015 Endothelin and the Renal MicrocirculationSeminars in Nephrology.  35:145-155. 2015
2015 Endothelin contributes to blunted renal autoregulation observed with a high-salt diet 2015
2014 Sphingosine-1-phosphate evokes unique segment-specific vasoconstriction of the renal microvasculatureJournal of the American Society of Nephrology.  25:1774-1785. 2014
2014 P2 receptors in renal autoregulation 2014
2013 Immunosuppression preserves renal autoregulatory function and microvascular P2X1 receptor reactivity in ANG II-hypertensive rats 2013
2011 Endothelin and the renal vasculature.Contributions to Nephrology.  172:35-49. 2011
2011 Endothelin and the renal vasculatureContributions to Nephrology.  172:35-49. 2011
2011 Role of adenosine 5′-triphosphate in regulating renal microvascular function and in hypertensionHypertension.  58:333-340. 2011
2011 P2X1 receptor-mediated vasoconstriction of afferent arterioles in angiotensin II-infused hypertensive rats fed a high-salt dietHypertension.  57:780-787. 2011
2010 Response to role of epithelial sodium channels in the renal myogenic response?Hypertension.  55. 2010
2010 Pentosan polysulfate treatment preserves renal autoregulation in ANG II-infused hypertensive rats via normalization of P2X1 receptor activation 2010
2009 Effect of epithelial sodium channel blockade on the myogenic response of rat juxtamedullary afferent arteriolesHypertension.  54:1062-1069. 2009
2007 P2X receptors as regulators of the renal microvasculatureTrends in Pharmacological Sciences.  28:646-652. 2007
2007 Purinoceptors in the kidneyExperimental Biology and Medicine.  232:715-726. 2007
2006 Delayed administration of darbepoetin or erythropoietin protects against ischemic acute renal injury and failureKidney International.  69:1806-1813. 2006
2006 Renal endothelial dysfunction and impaired autoregulation after ischemia-reperfusion injury result from excess nitric oxide 2006
2004 Angiotensin II facilitates autoregulation in the perfused mouse kidney: An optimized in vitro model for assessment of renal vascular and tubular functionNephrology.  9:288-296. 2004
2003 Facilitation of renal autoregulation by angiotensin II is mediated through modulation of nitric oxideActa Physiologica.  179:189-201. 2003

Education And Training

  • Doctor of Philosophy in Medical Scientist, 2004
  • Full Name

  • Zhengrong Guan