Positions

Selected Publications

Academic Article

Year Title Altmetric
2021 Scalable de Novo Genome Assembly Using a Pregel-Like Graph-Parallel SystemIEEE/ACM Transactions on Computational Biology and Bioinformatics.  18:731-744. 2021
2020 The effects of common structural variants on 3D chromatin structureBMC Genomics.  21. 2020
2020 MRLR: Unraveling high-resolution meiotic recombination by linked readsBioinformatics.  36:10-16. 2020
2020 Ozone and Particulate Matter Exposure and Alzheimer's Disease: A Review of Human and Animal StudiesJournal of Alzheimer's Disease.  76:807-824. 2020
2019 Megabase Length Hypermutation Accompanies Human Structural Variation at 17p11.2Cell.  176:1310-1324.e10. 2019
2018 Combining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detectionGenome Biology.  19. 2018
2018 Marker chromosome genomic structure and temporal origin implicate a chromoanasynthesis event in a family with pleiotropic psychiatric phenotypesHuman Mutation.  39:939-946. 2018
2018 Regenerative potential of neonatal porcine heartsCirculation.  138:2809-2816. 2018
2017 An Organismal CNV Mutator Phenotype Restricted to Early Human DevelopmentCell.  168:830-842.e7. 2017
2017 A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell LinesCell Systems.  5:485-497.e3. 2017
2016 Hotspot mutations delineating diverse mutational signatures and biological utilities across cancer typesBMC Genomics.  17. 2016
2015 Identification of variant-specific functions of PIK3CA by rapid phenotyping of rare mutationsCancer Research.  75:5341-5354. 2015
2015 ClinSeK: A targeted variant characterization framework for clinical sequencing 2015
2015 Clinical actionability enhanced through deep targeted sequencing of solid tumors 2015
2014 Towards accurate characterization of clonal heterogeneity based on structural variationBMC Bioinformatics.  15. 2014
2014 Trrap-dependent histone acetylation specifically regulates cell-cycle gene transcription to control neural progenitor fate decisionsCell Stem Cell.  14:632-643. 2014
2014 Ago2 facilitates Rad51 recruitment and DNA double-strand break repair by homologous recombinationCell Research.  24:532-541. 2014
2013 Pseudo-Sanger sequencing: Massively parallel production of long and near error-free reads using NGS technologyBMC Genomics.  14. 2013
2012 Rainbow: An integrated tool for efficient clustering and assembling RAD-seq readsBioinformatics.  28:2732-2737. 2012

Book

Year Title Altmetric
2020 Ozone and Particulate Matter Exposure and Alzheimer's Disease: A Review of Human and Animal Studies.  Ed. 8.  2020

Chapter

Year Title Altmetric
2021 Ozone and particulate matter exposure and Alzheimer's disease: A review of human and animal studies.  417-434. 2021

Education And Training

  • Univeristy of Texas MD Anderson Cancer Center Bioinformatics and Computational Biology, Postdoctoral Fellowship
  • Doctor of Social or Behavioral Sciences in Genome Sciences / Genomics, Chinese Academy of Medical Sciences and Peking Union Medical College 2013
  • Full Name

  • Zechen Chong