Year |
Title |
Altmetric |
2021
|
Early life and adult stress promote sex dependent changes in hypothalamic miRNAs and environmental enrichment prevents stress-induced miRNA and gene expression changes in rats.
BMC Genomics.
22.
2021
|
|
2021
|
Advances in novel molecular targets for antidepressants.
Progress in Neuro-Psychopharmacology and Biological Psychiatry.
104.
2021
|
|
2020
|
Elevated expression of unfolded protein response genes in the prefrontal cortex of depressed subjects: Effect of suicide.
Journal of Affective Disorders.
262:229-236.
2020
|
|
2020
|
MicroRNA mediators of early life stress vulnerability to depression and suicidal behavior.
Molecular Psychiatry.
25:308-320.
2020
|
|
2019
|
A Novel Animal Model for Studying Depression Featuring the Induction of the Unfolded Protein Response in Hippocampus.
Molecular Neurobiology.
56:8524-8536.
2019
|
|
2019
|
Co-expression network modeling identifies key long non-coding RNA and mRNA modules in altering molecular phenotype to develop stress-induced depression in rats.
Translational Psychiatry.
9.
2019
|
|
2019
|
Linking unfolded protein response to inflammation and depression: potential pathologic and therapeutic implications.
Molecular Psychiatry.
24:987-994.
2019
|
|
2019
|
Chronic Testosterone Increases Impulsivity and Influences the Transcriptional Activity of the Alpha-2A Adrenergic Receptor Signaling Pathway in Rat Brain.
Molecular Neurobiology.
56:4061-4071.
2019
|
|
2019
|
Role of HPA and the HPG Axis Interaction in Testosterone-Mediated Learned Helpless Behavior.
Molecular Neurobiology.
56:394-405.
2019
|
|
2018
|
MicroRNAs in depression and suicide: Recent insights and future perspectives.
Journal of Affective Disorders.
240:146-154.
2018
|
|
2018
|
Long Noncoding RNA-Associated Transcriptomic Changes in Resiliency or Susceptibility to Depression and Response to Antidepressant Treatment.
International Journal of Neuropsychopharmacology.
21:461-472.
2018
|
|
2018
|
Role of complex epigenetic switching in tumor necrosis factor-α upregulation in the prefrontal cortex of suicide subjects.
American Journal of Psychiatry.
175:262-274.
2018
|
|
2018
|
Unfolded protein response and associated alterations in toll-like receptor expression and interaction in the hippocampus of restraint rats.
Psychoneuroendocrinology.
89:185-193.
2018
|
|
2018
|
The concept of violent suicide, its underlying trait and neurobiology: A critical perspective.
European Neuropsychopharmacology.
28:243-251.
2018
|
|
2018
|
Interaction between early-life stress and FKBP5 gene variants in major depressive disorder and post-traumatic stress disorder: A systematic review and meta-analysis.
Journal of Affective Disorders.
225:422-428.
2018
|
|
2018
|
Understanding the Neuroepigenetic Constituents of Suicide Brain.
Progress in Molecular Biology and Translational Science.
157:233-262.
2018
|
|
2017
|
Altered miRNA expression network in locus coeruleus of depressed suicide subjects.
Scientific Reports.
7.
2017
|
|
2017
|
Transcriptional profiling of mitochondria associated genes in prefrontal cortex of subjects with major depressive disorder.
World Journal of Biological Psychiatry.
18:592-603.
2017
|
|
2017
|
Albumin Protein Cleavage Affects the Wear and Friction of Ultra-High Molecular Weight Polyethylene..
Lubricants.
5.
2017
|
|
2017
|
The recent progress in animal models of depression.
Progress in Neuro-Psychopharmacology and Biological Psychiatry.
77:99-109.
2017
|
|
2017
|
microRNA-124: a putative therapeutic target and biomarker for major depression.
Expert Opinion on Therapeutic Targets.
21:653-656.
2017
|
|
2017
|
DNA methylation and expression of stress related genes in PBMC of MDD patients with and without serious suicidal ideation.
Journal of Psychiatric Research.
89:115-124.
2017
|
|
2017
|
Cognitive flexibility impairment and reduced frontal cortex BDNF expression in the ouabain model of mania.
Neuroscience.
345:229-242.
2017
|
|
2017
|
Identification of MicroRNA-124-3p as a Putative Epigenetic Signature of Major Depressive Disorder.
Neuropsychopharmacology.
42:864-875.
2017
|
|
2017
|
The life span model of suicide and its neurobiological foundation.
Frontiers in Neuroscience.
11.
2017
|
|
2017
|
Animal models to improve our understanding and treatment of suicidal behavior.
Translational Psychiatry.
7.
2017
|
|
2017
|
Understanding epigenetic architecture of suicide neurobiology: A critical perspective.
Neuroscience and Biobehavioral Reviews.
72:10-27.
2017
|
|
2016
|
Dissecting bipolar disorder complexity through epigenomic approach.
Molecular Psychiatry.
21:1490-1498.
2016
|
|
2016
|
Altered expression of endoplasmic reticulum stress associated genes in hippocampus of learned helpless rats: Relevance to depression pathophysiology.
Frontiers in Pharmacology.
6.
2016
|
|
2016
|
Pathogenetic and therapeutic applications of microRNAs in major depressive disorder.
Progress in Neuro-Psychopharmacology and Biological Psychiatry.
64:341-348.
2016
|
|
2016
|
Altered ERK1/2 signaling in the brain of learned helpless rats: Relevance in vulnerability to developing stress-induced depression.
Neural Plasticity.
2016.
2016
|
|
2015
|
Chronic corticosterone-mediated dysregulation of microRNA network in prefrontal cortex of rats: Relevance to depression pathophysiology.
Translational Psychiatry.
5.
2015
|
|
2015
|
Noncoding RNAs and neurobehavioral mechanisms in psychiatric disease.
Molecular Psychiatry.
20:677-684.
2015
|
|
2015
|
Serotonergic and Noradrenergic Neurotransmitter Systems in Suicide.
Advances in Biological Psychiatry -Basel-.
30:21-36.
2015
|
|
2014
|
Expression of micrornas and other small RNAs in prefrontal cortex in schizophrenia, bipolar disorder and depressed subjects.
PLoS ONE.
9.
2014
|
|
2014
|
Alteration of cyclic-AMP response element binding protein in the postmortem brain of subjects with bipolar disorder and schizophrenia.
Journal of Affective Disorders.
152-154:326-333.
2014
|
|
2014
|
Emerging role of microRNAs in major depressive disorder: Diagnosis and therapeutic implications.
Dialogues in Clinical Neuroscience.
16:43-61.
2014
|
|
2014
|
Enoxacin elevates microRNA levels in rat frontal cortex and prevents learned helplessness.
Frontiers in Psychiatry.
5.
2014
|
|
2014
|
Hippocampal neurogenesis, neurotrophic factors and depression: Possible therapeutic targets?
2014
|
|
2014
|
The involvement of micrornas in major depression, suicidal behavior, and related disorders: A focus on miR-185 and miR-491-3p.
Cellular and Molecular Neurobiology.
34:17-30.
2014
|
|
2014
|
Toll-like receptors in the depressed and suicide brain.
Journal of Psychiatric Research.
53:62-68.
2014
|
|
2013
|
MicroRNAs: Fundamental regulators of gene expression in major affective disorders and suicidal behavior?.
Frontiers in Cellular Neuroscience.
6.
2013
|
|
2013
|
Region-specific alterations in glucocorticoid receptor expression in the postmortem brain of teenage suicide victims.
Psychoneuroendocrinology.
38:2628-2639.
2013
|
|
2013
|
The role of neuropeptides in suicidal behavior: A systematic review.
BioMed Research International.
2013.
2013
|
|
2013
|
Altered Wnt signalling in the teenage suicide brain: Focus on glycogen synthase kinase-3β and β-catenin.
International Journal of Neuropsychopharmacology.
16:945-955.
2013
|
|
2013
|
Pharmacological properties of glutamatergic drugs targeting NMDA receptors and their application in major depression.
Current Pharmaceutical Design.
19:1898-1922.
2013
|
|
2013
|
Adult medication-free schizophrenic patients exhibit long-chain omega-3 fatty acid deficiency: Implications for cardiovascular disease risk.
Cardiovascular Psychiatry and Neurology.
2013.
2013
|
|
2013
|
Involvement of brain-derived neurotrophic factor in late-life depression.
American Journal of Geriatric Psychiatry.
21:433-449.
2013
|
|
2013
|
Lower docosahexaenoic acid concentrations in the postmortem prefrontal cortex of adult depressed suicide victims compared with controls without cardiovascular disease.
Journal of Psychiatric Research.
47:1187-1191.
2013
|
|
2013
|
microRNAs as Biomarker in Depression Pathogenesis..
Annals of Psychiatry and Mental Health.
1:1003.
2013
|
|
2012
|
The role of microRNAs in synaptic plasticity, major affective disorders and suicidal behavior.
Neuroscience Research.
73:179-190.
2012
|
|
2012
|
MicroRNA expression is down-regulated and reorganized in prefrontal cortex of depressed suicide subjects.
PLoS ONE.
7.
2012
|
|
2012
|
Proinflammatory cytokines in the prefrontal cortex of teenage suicide victims.
Journal of Psychiatric Research.
46:57-63.
2012
|
|
2011
|
MicroRNA expression in rat brain exposed to repeated inescapable shock: Differential alterations in learned helplessness vs. non-learned helplessness.
International Journal of Neuropsychopharmacology.
14:1315-1325.
2011
|
|
2011
|
Evidence demonstrating role of microRNAs in the etiopathology of major depression.
Journal of Chemical Neuroanatomy.
42:142-156.
2011
|
|
2011
|
Elucidating biological risk factors in suicide: Role of protein kinase A.
Progress in Neuro-Psychopharmacology and Biological Psychiatry.
35:831-841.
2011
|
|
2011
|
Glycosides, depression and suicidal behaviour: The role of glycoside-linked proteins.
Molecules.
16:2688-2713.
2011
|
|
2011
|
Cyclic-AMP response element binding protein (CREB) in the neutrophils of depressed patients.
Psychiatry Research.
185:108-112.
2011
|
|
2010
|
Selective deficits in erythrocyte docosahexaenoic acid composition in adult patients with bipolar disorder and major depressive disorder.
Journal of Affective Disorders.
126:303-311.
2010
|
|
2010
|
What can post-mortem studies tell us about the pathoetiology of suicide?.
Future Neurology.
5:701-720.
2010
|
|
2010
|
Modulation in Activation and Expression of Phosphatase and Tensin Homolog on Chromosome Ten, Akt1, and 3-Phosphoinositide-Dependent Kinase 1: Further Evidence Demonstrating Altered Phosphoinositide 3-Kinase Signaling in Postmortem Brain of Suicide Subjects.
Biological Psychiatry.
67:1017-1025.
2010
|
|
2010
|
Brain-derived neurotrophic factor gene and protein expression in pediatric and adult depressed subjects.
Progress in Neuro-Psychopharmacology and Biological Psychiatry.
34:645-651.
2010
|
|
2010
|
Glycogen synthase kinase-3β in the platelets of patients with mood disorders: Effect of treatment.
Journal of Psychiatric Research.
44:143-148.
2010
|
|
2010
|
Brain-derived neurotrophic factor and suicide pathogenesis..
Annals of Medicine.
42:87-96.
2010
|
|
2009
|
Aberrant extracellular signal-regulated kinase (ERK)1/2 signalling in suicide brain: Role of ERK kinase 1 (MEK1).
International Journal of Neuropsychopharmacology.
12:1337-1354.
2009
|
|
2009
|
Neurotrophin Receptor Activation and Expression in Human Postmortem Brain: Effect of Suicide.
Biological Psychiatry.
65:319-328.
2009
|
|
2009
|
GSK-3β gene expression in human postmortem brain: Regional distribution, effects of age and suicide.
Neurochemical Research.
34:274-285.
2009
|
|
2009
|
Brain-derived neurotrophic factor: Role in depression and suicide.
Neuropsychiatric Disease and Treatment.
5:433-449.
2009
|
|
2009
|
Fatty acid composition of the postmortem prefrontal cortex of adolescent male and female suicide victims
2009
|
|
2009
|
Pharmacological Characterization of Inositol 1,4,5-tris Phosphate Receptors in Human Platelet Membranes..
Cardiovascular Psychiatry and Neurology.
2009:618586.
2009
|
|
2008
|
Brain-derived neurotrophic factor and tyrosine kinase B receptor signalling in post-mortem brain of teenage suicide victims.
International Journal of Neuropsychopharmacology.
11:1047-1061.
2008
|
|
2008
|
Lower phosphoinositide 3-kinase (PI 3-kinase) activity and differential expression levels of selective catalytic and regulatory PI 3-kinase subunit isoforms in prefrontal cortex and hippocampus of suicide subjects.
Neuropsychopharmacology.
33:2324-2340.
2008
|
|
2008
|
Postmortem brain tissue of depressed suicides reveals increased Gsα localization in lipid raft domains where it is less likely to activate adenylyl cyclase
2008
|
|
2008
|
Adenylyl cyclase-cyclicAMP signaling in mood disorders: role of the crucial phosphorylating enzyme protein kinase A..
Neuropsychiatric Disease and Treatment.
4:161-176.
2008
|
|
2008
|
5-Lipoxygenase in the Prefrontal Cortex of Suicide Victims..
The open neuropsychopharmacology journal.
1:1-5.
2008
|
|
2008
|
Adenylyl cyclase-cyclicAMP signaling in mood disorders: Role of the crucial phosphorylating enzyme protein kinase A.
Neuropsychiatric Disease and Treatment.
4:161-176.
2008
|
|
2008
|
Brain-derived neurotrophic factor gene expression in pediatric bipolar disorder: Effects of treatment and clinical response.
Journal of the American Academy of Child and Adolescent Psychiatry.
47:1077-1085.
2008
|
|
2008
|
Decreased protein kinase C (PKC) in platelets of pediatric bipolar patients: Effect of treatment with mood stabilizing drugs.
Journal of Psychiatric Research.
42:106-116.
2008
|
|
2007
|
Aberrant extracellular signal-regulated kinase (ERK) 5 signaling in hippocampus of suicide subjects.
Neuropsychopharmacology.
32:2338-2350.
2007
|
|
2007
|
Role of protein kinase A in the etiology of suicide: Evidence from human postmortem brain and preclinical studies
2007
|
|
2007
|
Cyclic AMP response element-binding protein in post-mortem brain of teenage suicide victims: Specific decrease in the prefrontal cortex but not the hippocampus.
International Journal of Neuropsychopharmacology.
10:621-629.
2007
|
|
2007
|
Noradrenergic function in suicide.
Archives of Suicide Research.
11:235-246.
2007
|
|
2006
|
Differential and brain region-specific regulation of Rap-1 and Epac in depressed suicide victims.
Archives of General Psychiatry.
63:639-648.
2006
|
|
2006
|
Hippocampal cell proliferation regulation by repeated stress and antidepressants.
NeuroReport.
17:863-867.
2006
|
|
2006
|
Antidepressants reverse corticosterone-mediated decrease in brain-derived neurotrophic factor expression: Differential regulation of specific exons by antidepressants and corticosterone.
Neuroscience.
139:1017-1029.
2006
|
|
2006
|
Monoamine receptors and signal transduction mechanisms in suicide.
Current Psychiatry Reviews.
2:51-75.
2006
|
|
2006
|
Regional distribution and relative abundance of serotonin2c receptors in human brain: Effect of suicide.
Neurochemical Research.
31:167-176.
2006
|
|
2006
|
ERK MAP kinase signaling in post-mortem brain of suicide subjects: Differential regulation of upstream Raf kinases Raf-1 and B-Raf.
Molecular Psychiatry.
11:86-98.
2006
|
|
2005
|
Suicide brain is associated with decreased expression of neurotrophins.
Biological Psychiatry.
58:315-324.
2005
|
|
2005
|
Brain region specific alterations in the protein and mRNA levels of protein kinase A subunits in the post-mortem brain of teenage suicide victims.
Neuropsychopharmacology.
30:1548-1556.
2005
|
|
2005
|
The regional and cellular expression profile of the melatonin receptor MT1 in the central dopaminergic system.
Brain Research.
136:45-53.
2005
|
|
2005
|
Focus on protein kinase A and protein kinase C, critical components of signal transduction system, in mood disorders and suicide.
International Journal of Neuropsychopharmacology.
8:1-4.
2005
|
|
2005
|
Single and repeated stress-induced modulation of phospholipase C catalytic activity and expression: Role in LH behavior.
Neuropsychopharmacology.
30:473-483.
2005
|
|
2005
|
Chapter 5.1 The intracellular signaling cascade and stress.
Techniques in the Behavioral and Neural Sciences.
15:643-663.
2005
|
|
2005
|
Differential regulation of serotonin (5HT)2A receptor mRNA and protein levels after single and repeated stress in rat brain: Role in learned helplessness behavior.
Neuropharmacology.
48:204-214.
2005
|
|
2004
|
Altered protein kinase A in brain of learned helpless rats: Effects of acute and repeated stress.
Biological Psychiatry.
56:30-40.
2004
|
|
2004
|
Decreased catalytic activity and expression of protein kinase C isozymes in teenage suicide victims: A postmortem brain study.
Archives of General Psychiatry.
61:685-693.
2004
|
|
2004
|
Protein kinase a in postmortem brain of depressed suicide victims: Altered expression of specific regulatory and catalytic subunits.
Biological Psychiatry.
55:234-243.
2004
|
|
2003
|
Serotonin receptors in platelets of bipolar and schizoaffective patients: Effect of lithium treatment.
Psychopharmacology.
170:115-123.
2003
|
|
2003
|
Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects.
Archives of General Psychiatry.
60:804-815.
2003
|
|
2003
|
Abnormal expression and functional characteristics of cyclic adenosine monophosphate response element binding protein in postmortem brain of suicide subjects.
Archives of General Psychiatry.
60:273-282.
2003
|
|
2003
|
Altered expression and phosphorylation of myristoylated alanine-rich C kinase substrate (MARCKS) in postmortem brain of suicide victims with or without depression.
Journal of Psychiatric Research.
37:421-432.
2003
|
|
2002
|
Erratum: mRNA and protein expression of selective alpha subunits of G proteins are abnormal in prefrontal cortex of suicide victims (Neuropsychopharmacology (October 2002) 27:4 (499-517) PII:S0893133X02003354).
Neuropsychopharmacology.
27:1092.
2002
|
|
2002
|
mRNA and protein expression of selective alpha subunits of G proteins are abnormal in prefrontal cortex of suicide victims.
Neuropsychopharmacology.
27:499-517.
2002
|
|
2002
|
Differential effects of haloperidol and clozapine on [3H]cAMP binding, protein kinase A (PKA) activity, and mRNA and protein expression of selective regulatory and catalytic subunit isoforms of PKA in rat brain.
Journal of Pharmacology and Experimental Therapeutics.
301:197-209.
2002
|
|
2002
|
Higher expression of serotonin 5-HT2A receptors in the postmortem brains of teenage suicide victims.
American Journal of Psychiatry.
159:419-429.
2002
|
|
2002
|
Protein kinase C and phospholipase C activity and expression of their specific isozymes is decreased and expression of MARCKS is increased in platelets of bipolar but not in unipolar patients.
Neuropsychopharmacology.
26:216-228.
2002
|
|
2002
|
Antidepressants reduce phosphoinositide-specific phospholipase C (PI-PLC) activity and the mRNA and protein expression of selective PLC β1 isozyme in rat brain.
Neuropharmacology.
43:1269-1279.
2002
|
|
2002
|
[3H]cAMP binding sites and protein kinase A activity in the prefrontal cortex of suicide victims.
American Journal of Psychiatry.
159:66-73.
2002
|
|
2001
|
Hyperactive phosphoinositide signaling pathway in platelets of depressed patients: Effect of desipramine treatment.
Psychiatry Research.
105:23-32.
2001
|
|
2001
|
Reduced activation and expression of ERK1/2 MAP kinase in the post-mortem brain of depressed suicide subjects.
Journal of Neurochemistry.
77:916-928.
2001
|
|
2001
|
Glucocorticoid receptors are required for up-regulation of neuronal 5-lipoxygenase (5LOX) expression by dexamethasone..
The FASEB Journal.
15:1792-1794.
2001
|
|
2000
|
Modifications in the phosphoinositide signaling pathway by adrenal glucocorticoids in rat brain: Focus on phosphoinositide-specific phospholipase C and inositol 1,4,5-trisphosphate.
Journal of Pharmacology and Experimental Therapeutics.
295:244-254.
2000
|
|
2000
|
Adrenal glucocorticoids modulate [3H]cyclic AMP binding to protein kinase A (PKA), cyclic AMP-dependent PKA activity, and protein levels of selective regulatory and catalytic subunit isoforms of PKA in rat brain.
Journal of Pharmacology and Experimental Therapeutics.
294:103-116.
2000
|
|
2000
|
Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: A postmortem brain study.
Archives of General Psychiatry.
57:1061-1069.
2000
|
|
1999
|
Low phosphoinositide-specific phospholipase C activity and expression of phospholipase C β1 protein in the prefrontal cortex of teenage suicide subjects.
American Journal of Psychiatry.
156:1895-1901.
1999
|
|
1999
|
Effects of treatment with haloperidol, chlorpromazine, and clozapine on protein kinase C (PKC) and phosphoinositide-specific phospholipase C (PI-PLC) activity and on mRNA and protein expression of PKC and PLC isozymes in rat brain.
Journal of Pharmacology and Experimental Therapeutics.
291:688-704.
1999
|
|
1999
|
Glucocorticoids stimulate inflammatory 5-lipoxygenase gene expression and protein translocation in the brain.
Journal of Neurochemistry.
73:693-699.
1999
|
|
1999
|
Repeated administration of dexamethasone increases phosphoinositide- specific phospholipase C activity and mRNA and protein expression of the phospholipase C β1 isozyme in rat brain.
Journal of Neurochemistry.
73:780-790.
1999
|
|
1999
|
The phenotypic characteristics of heterozygous reeler mouse.
NeuroReport.
10:1329-1334.
1999
|
|
1999
|
Administration of dexamethasone up-regulates protein kinase C activity and the expression of γ and ε protein kinase C isozymes in the rat brain.
Journal of Neurochemistry.
72:380-387.
1999
|
|
1998
|
A decrease of reelin expression as a putative vulnerability factor in schizophrenia
1998
|
|
1998
|
Quantitation of 5HT(2A) receptor mRNA in human postmortem brain using competitive RT-PCR.
NeuroReport.
9:3761-3765.
1998
|
|
1998
|
Protein kinase C in platelets of depressed patients.
Biological Psychiatry.
44:909-911.
1998
|
|
1998
|
Elevated [3H]inositol 1,4,5-trisphosphate binding sites and expressed inositol 1,4,5-trisphosphate receptor protein level in platelets of depressed patients.
Psychopharmacology.
138:47-54.
1998
|
|
1997
|
Effects of subchronic administration of antidepressants and anxiolytics on levels of the α subunits of G proteins in the rat brain.
Journal of Neural Transmission.
104:747-760.
1997
|
|
1997
|
Protein kinase C in the postmortem brain of teenage suicide victims.
Neuroscience Letters.
228:111-114.
1997
|
|
1996
|
Pharmacological characterization of inositol 1,4,5trisphosphate receptors in human platelet membranes: Effects of calcium and cyclic amp.
The FASEB Journal.
10.
1996
|
|
1995
|
Platelet serotonin-2A receptors: A potential biological marker for suicidal behavior.
American Journal of Psychiatry.
152:850-855.
1995
|
|
1993
|
Chronic ethanol consumption decreases the phorbol ester binding to membranal but not cytosolic protein kinase C in rat brain.
Alcohol.
10:259-262.
1993
|
|