| Year |
Title |
Altmetric |
| 2022
|
Novel Allosteric Inhibitor-Derived AKT Proteolysis Targeting Chimeras (PROTACs) Enable Potent and Selective AKT Degradation in KRAS/BRAF Mutant Cells..
Journal of Medicinal Chemistry.
65:14237-14260.
2022
|
|
| 2022
|
A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma..
Nature Communications.
13:6041.
2022
|
|
| 2022
|
Discovery of Potent, Selective, and In Vivo Efficacious AKT Kinase Protein Degraders via Structure-Activity Relationship Studies..
Journal of Medicinal Chemistry.
65:3644-3666.
2022
|
|
| 2021
|
Design, Synthesis, and Evaluation of Potent, Selective, and Bioavailable AKT Kinase Degraders..
Journal of Medicinal Chemistry.
64:18054-18081.
2021
|
|
| 2021
|
AKT Degradation Selectively Inhibits the Growth of PI3K/PTEN Pathway-Mutant Cancers with Wild-Type KRAS and BRAF by Destabilizing Aurora Kinase B..
Cancer Discovery.
11:3064-3089.
2021
|
|
| 2017
|
p53 Maintains Baseline Expression of Multiple Tumor Suppressor Genes..
Molecular Cancer Research.
15:1051-1062.
2017
|
|
| 2016
|
Upregulation of lactate dehydrogenase a by 14-3-3ζ leads to increased glycolysis critical for breast cancer initiation and progression..
Oncotarget.
7:35270-35283.
2016
|
|
| 2016
|
Downregulation of GLUT4 contributes to effective intervention of estrogen receptor-negative/HER2-overexpressing early stage breast disease progression by lapatinib..
American Journal of Cancer Research.
6:981-995.
2016
|
|
| 2015
|
14-3-3ζ turns TGF-β's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2..
Cancer Cell.
27:177-192.
2015
|
|
| 2012
|
Methylation of HIN-1, RASSF1A, RIL and CDH13 in breast cancer is associated with clinical characteristics, but only RASSF1A methylation is associated with outcome..
BMC Cancer.
12:243.
2012
|
|
| 2012
|
Overexpression of 14-3-3ζ in cancer cells activates PI3K via binding the p85 regulatory subunit..
Oncogene.
31:897-906.
2012
|
|
| 2012
|
Evidence that GTP-binding domain but not catalytic domain of transglutaminase 2 is essential for epithelial-to-mesenchymal transition in mammary epithelial cells..
Breast Cancer Research.
14:R4.
2012
|
|
| 2011
|
Evidence that aberrant expression of tissue transglutaminase promotes stem cell characteristics in mammary epithelial cells..
PLoS One.
6:e20701.
2011
|
|
| 2010
|
Tissue transglutaminase promotes drug resistance and invasion by inducing mesenchymal transition in mammary epithelial cells..
PLoS One.
5:e13390.
2010
|
|
| 2010
|
Tumor suppressor genes are frequently methylated in lymph node metastases of breast cancers..
BMC Cancer.
10:378.
2010
|
|
| 2009
|
Upregulation of neutrophil gelatinase-associated lipocalin by ErbB2 through nuclear factor-kappaB activation..
Cancer Research.
69:9163-9168.
2009
|
|
| 2006
|
Isolation and RNA1 nucleotide sequence determination of a new insect nodavirus from Pieris rapae larvae in Wuhan city, China..
Virus Research.
120:28-35.
2006
|
|
