Positions

Overview

  • Medical Director, Advanced Lung Diseases
    Medical Director, Adult ECMO

    • Selected Publications

    Academic Article

    Year Title Altmetric
    2021 Continuous renal replacement therapy in patients treated with extracorporeal membrane oxygenation.  Seminars in Dialysis.  34:537-549. 2021
    2021 Extracorporeal photopheresis to attenuate decline in lung function due to refractory obstructive allograft dysfunction.  Transfusion Medicine.  31:292-302. 2021
    2021 Risk of primary graft dysfunction following lung transplantation in selected adults with connective tissue disease-associated interstitial lung disease 2021
    2021 Citrullinated vimentin mediates development and progression of lung fibrosis.  Science Translational Medicine.  13. 2021
    2021 Extracorporeal membrane oxygenation in patients with severe respiratory failure from COVID-19.  Intensive Care Medicine.  47:208-221. 2021
    2021 Positive Retrospective SARS-CoV-2 Testing in a Case of Acute Respiratory Distress Syndrome of Unknown Etiology. 2021
    2021 Recipient Age Impacts Long-Term Survival in Adult Subjects with Cystic Fibrosis after Lung Transplantation.  Annals of the American Thoracic Society.  18:44-50. 2021
    2021 Supportive care of right ventricular failure due to fat embolism syndrome.  Respiratory Medicine Case Reports.  34. 2021
    2020 International Society for Heart and Lung Transplantation consensus statement for the standardization of bronchoalveolar lavage in lung transplantation 2020
    2020 Differences in airway microbiome and metabolome of single lung transplant recipients.  Respiratory Research.  21. 2020
    2020 Center and Donor Factors Associated with Discrepant Responses to Donor Lung Offers 2020
    2020 Implications of ECMO Bridging and Salvage Strategies on Mortality and PGD 2020
    2020 Multi-Center Validation of a Consensus-Based Scoring Guide for Evaluating Donor Lung Offers 2020
    2020 Pulmonary artery enlargement is associated with pulmonary hypertension and decreased survival in severe cystic fibrosis: A cohort study.  PLoS ONE.  15. 2020
    2019 Lung Transplantation for Cystic Fibrosis and Non-cystic Fibrosis Bronchiectasis: A Single-Center Experience.  Transplantation Proceedings.  51:2029-2034. 2019
    2019 Clinical outcomes of paramyxovirus infections in lung transplant recipients treated with oral Ribavirin: A two-center case series 2019
    2018 Distal airway microbiome is associated with immunoregulatory myeloid cell responses in lung transplant recipients 2018
    2018 Cell-free hemoglobin promotes primary graft dysfunction through oxidative lung endothelial injury.  JCI insight.  3. 2018
    2018 Quantitative evidence for revising the definition of primary graft dysfunction after lung transplant.  American Journal of Respiratory and Critical Care Medicine.  197:235-243. 2018
    2017 Clinical risk factors and prognostic model for primary graft dysfunction after lung transplantation in patients with pulmonary hypertension.  Annals of the American Thoracic Society.  14:1514-1522. 2017
    2017 Report of the ISHLT Working Group on primary lung graft dysfunction Part IV: Prevention and treatment: A 2016 Consensus Group statement of the International Society for Heart and Lung Transplantation 2017
    2017 Characteristics of lung allocation score exception requests submitted to the national Lung Review Board 2017
    2016 Use of a novel pulmonary artery cannula to provide extracorporeal membrane oxygenation as a bridge to lung transplantation 2016
    2016 Flexible bronchoscopy is safe and effective in adult subjects supported with extracorporeal membrane oxygenation 2016
    2016 The relationship between plasma lipid peroxidation products and primary graft dysfunction after lung transplantation is modified by donor smoking and reperfusion hyperoxia 2016
    2016 Protein Quantitative Trait Loci Analysis Identifies Genetic Variation in the Innate Immune Regulator TOLLIP in Post-Lung Transplant Primary Graft Dysfunction Risk.  American Journal of Transplantation.  16:833-840. 2016
    2016 Automated rotational percussion bed and bronchoscopy improves respiratory mechanics and oxygenation in ARDS patients supported with extracorporeal membrane oxygenation.  ASAIO Journal.  62:e27-e29. 2016
    2015 Assessing continuous renal replacement therapy as a rescue strategy in cardiorenal syndrome 1.  Clinical Kidney Journal.  8:87-92. 2015
    2015 Use of ECMO in the management of severe acute respiratory distress syndrome: A survey of academic medical centers in the United States.  ASAIO Journal.  61:556-563. 2015
    2015 Unexplained hemolysis in patients undergoing ECMO: Beware of hypertriglyceridemia.  Perfusion.  30:465-468. 2015
    2015 Successful treatment of severe carbon monoxide poisoning and refractory shock using extracorporeal membrane oxygenation 2015
    2015 Objective Estimates Improve Risk Stratification for Primary Graft Dysfunction after Lung Transplantation.  American Journal of Transplantation.  15:2188-2196. 2015
    2015 Pulmonary endarterectomy for pulmonary hypertension from septic emboli.  Annals of Thoracic Surgery.  99:1814-1816. 2015
    2015 Neutrophil extracellular traps are pathogenic in primary graft dysfunction after lung transplantation.  American Journal of Respiratory and Critical Care Medicine.  191:455-463. 2015
    2015 Lung size mismatch and primary graft dysfunction after bilateral lung transplantation 2015
    2015 Extracorporeal membrane oxygenation after liver transplantation in a patient with hepatopulmonary syndrome and an atrial septal defect 2015
    2015 Modern use of extracorporeal life support in pregnancy and postpartum.  ASAIO Journal.  61:110-114. 2015
    2014 Characteristics of patients with pulmonary venoocclusive disease awaiting transplantation.  Annals of the American Thoracic Society.  11:1411-1418. 2014
    2014 Plasma complement levels are associated with primary graft dysfunction and mortality after lung transplantation.  American Journal of Respiratory and Critical Care Medicine.  189:1564-1567. 2014
    2014 Genetic variation in the prostaglandin E2 pathway is associated with primary graft dysfunction.  American Journal of Respiratory and Critical Care Medicine.  189:567-575. 2014
    2014 Preoperative plasma club (Clara) cell secretory protein levels are associated with primary graft dysfunction after lung transplantation.  American Journal of Transplantation.  14:446-452. 2014
    2014 A continuous veno-venous hemofiltration protocol with anticoagulant citrate dextrose formula A and a calcium-containing replacement fluid 2014
    2014 Acute demyelinating polyneuropathy after lung transplantation: guillain-barré syndrome or tacrolimus toxicity?.  Case Reports in Transplantation.  2014:685010. 2014
    2014 CT scan-measured pulmonary artery to aorta ratio and echocardiography for detecting pulmonary hypertension in severe COPD.  Chest.  145:824-832. 2014
    2014 Successful pulmonary thromboendarterectomy in a patient with sickle cell disease treated with a single preoperative red blood cell exchange.  Transfusion.  54:1901-1902. 2014
    2014 Thromboendarterectomy for chronic thromboembolic pulmonary hypertension in hereditary hemorrhagic telangiectasia.  American Journal of Respiratory and Critical Care Medicine.  189:112-114. 2014
    2013 Disparities in lung transplantation before and after introduction of the lung allocation score 2013
    2013 Clinical risk factors for primary graft dysfunction after lung transplantation.  American Journal of Respiratory and Critical Care Medicine.  187:527-534. 2013
    2013 Latent class analysis identifies distinct phenotypes of primary graft dysfunction after lung transplantation.  Chest.  144:616-622. 2013
    2012 Elevated Plasma Angiopoietin-2 Levels and Primary Graft Dysfunction after Lung Transplantation.  PLoS ONE.  7. 2012
    2012 Advances in continuous renal replacement therapy: Citrate anticoagulation update.  Blood Purification.  34:88-93. 2012
    2012 Variation in PTX3 is associated with primary graft dysfunction after lung transplantation.  American Journal of Respiratory and Critical Care Medicine.  186:546-552. 2012
    2012 A panel of lung injury biomarkers enhances the definition of primary graft dysfunction (PGD) after lung transplantation 2012
    2012 Regional citrate anticoagulation for continuous renal replacement therapy: The better alternative?.  American Journal of Kidney Diseases.  59:745-747. 2012
    2012 Solute clearance in CRRT: Prescribed dose versus actual delivered dose.  Nephrology Dialysis Transplantation.  27:952-956. 2012
    2011 Salvaging the dehisced lung transplant bronchial anastomosis with homograft aorta.  Interactive Cardiovascular and Thoracic Surgery.  13:666-668. 2011
    2011 Elevated plasma long pentraxin-3 levels and primary graft dysfunction after lung transplantation for idiopathic pulmonary fibrosis.  American Journal of Transplantation.  11:2517-2522. 2011
    2011 Obesity and primary graft dysfunction after lung transplantation: The lung transplant outcomes group obesity study.  American Journal of Respiratory and Critical Care Medicine.  184:1055-1061. 2011
    2011 Effect of single vs bilateral lung transplantation on plasma surfactant protein D levels in idiopathic pulmonary fibrosis.  Chest.  140:489-496. 2011
    2011 Elevated plasma Clara cell secretory protein concentration is associated with high-grade primary graft dysfunction.  American Journal of Transplantation.  11:561-567. 2011
    2011 Management of complications in renal replacement therapy.  Seminars in Dialysis.  24:164-168. 2011
    2011 Elevated pulmonary artery pressure is a risk factor for primary graft dysfunction following lung transplantation for idiopathic pulmonary fibrosis.  Chest.  139:782-787. 2011
    2010 Construct validity of the definition of primary graft dysfunction after lung transplantation 2010
    2009 Plasma levels of receptor for advanced glycation end products, blood transfusion, and risk of primary graft dysfunction.  American Journal of Respiratory and Critical Care Medicine.  180:1010-1015. 2009
    2009 The presence of a matrix-derived neutrophil chemoattractant in bronchiolitis obliterans syndrome after lung transplantation.  Journal of Immunology.  182:4423-4431. 2009
    2009 Anticoagulation for continuous renal replacement therapy.  Seminars in Dialysis.  22:141-145. 2009
    2009 Plasma cytokines and chemokines in primary graft dysfunction post-lung transplantation.  American Journal of Transplantation.  9:389-396. 2009
    2008 Bronchiolitis obliterans syndrome and survival following lung transplantation for patients with sarcoidosis 2008
    2008 Risk factors and impact of chronic obstructive pulmonary disease in candidates for liver transplantation 2008
    2008 The epidemiology of severe acute kidney injury: From BEST to PICARD, in acute kidney injury: New concepts 2008
    2008 Standard versus high-dose CVVHDF for ICU-related acute renal failure.  Journal of the American Society of Nephrology.  19:1233-1238. 2008
    2008 Impact of Hepatopulmonary Syndrome on Quality of Life and Survival in Liver Transplant Candidates.  Gastroenterology.  135:1168-1175. 2008
    2007 Plasma intercellular adhesion molecule-1 and von Willebrand factor in primary graft dysfunction after lung transplantation.  American Journal of Transplantation.  7:2573-2578. 2007
    2006 Citrate-Based Replacement Solutions with Continuous Venovenous Hemofiltration: Not as Simple as It Sounds.  American Journal of Kidney Diseases.  47:1086. 2006
    2006 A practical citrate anticoagulation continuous venovenous hemodiafiltration protocol for metabolic control and high solute clearance..  Clinical Journal of the American Society of Nephrology.  1:79-87. 2006
    2005 Multi-organ transplantation: Is there a protective effect against acute and chronic rejection? 2005
    2005 The intensive care unit oxygen challenge should not be used for donor lung function decision-making 2005
    2005 Sternal approximation for bilateral anterolateral transsternal thoracotomy for lung transplantation.  Annals of Thoracic Surgery.  79. 2005
    2004 Validation of a multistage asthma case-detection procedure for elementary school children.  Pediatrics.  114. 2004

    Chapter

    Year Title Altmetric
    2017 Anticoagulation for Continuous Renal Replacement Therapy.  380-385.e1. 2017
    2016 Complications of continuous renal replacement therapy (CRRT).  211-219. 2016

    Research Overview

  • Lung transplantation, mechanical circulatory support, pulmonary embolism

    • Principal Investigator On

    Investigator On

    Education And Training

  • UAB Hospital, Internship
  • UAB Hospital, Residency
  • UAB Hospital, Postdoctoral Fellowship
  • Doctor of Medicine, Louisiana State University System : University of New Orleans 1994

    • Full Name

  • Keith Wille