Positions

Selected Publications

Academic Article

Year Title Altmetric
2022 Excitation and Inhibition Imbalance in Rett Syndrome.  Frontiers in Neuroscience.  16. 2022
2020 Dysfunction of the corticostriatal pathway in autism spectrum disorders.  Journal of Neuroscience Research.  98:2130-2147. 2020
2019 Differences in GluN2B-containing NMDA receptors result in distinct long-term plasticity at ipsilateral versus contralateral cortico-striatal synapses.  eNeuro.  6. 2019
2017 A small-molecule TrkB ligand restores hippocampal synaptic plasticity and object location memory in Rett syndrome mice.  Disease Models and Mechanisms.  10:837-845. 2017
2016 Excitatory synapses are stronger in the hippocampus of Rett syndrome mice due to altered synaptic trafficking of AMPA-type glutamate receptors 2016
2015 Excitation/inhibition imbalance and impaired synaptic inhibition in hippocampal area CA3 of Mecp2 knockout mice 2015
2014 BDNF deregulation in Rett syndrome.  Neuropharmacology.  76:737-746. 2014
2013 Identification of a Functionally Distinct Truncated BDNF mRNA Splice Variant and Protein in Trachemys scripta elegans.  PLoS One.  8. 2013
2013 Hyperforin modulates dendritic spine morphology in hippocampal pyramidal neurons by activating Ca2+-permeable TRPC6 channels 2013
2013 Recent progress in Rett syndrome and MECP2 dysfunction: Assessment of potential treatment options.  Future Neurology.  8:21-28. 2013
2012 Activity-dependent BDNF release and TRPC signaling is impaired in hippocampal neurons of Mecp2 mutant mice 2012
2012 Rapid enrichment of presynaptic protein in boutons undergoing classical conditioning is mediated by brain-derived neurotrophic factor.  Neuroscience.  203:50-58. 2012
2012 Beyond Widespread Mecp2 Deletions to Model Rett Syndrome: Conditional Spatio-Temporal Knockout, Single-Point Mutations and Transgenic Rescue Mice..  Autism - Open Access.  2012:5. 2012
2011 Transsynaptic EphB/Ephrin-B signaling regulates growth of presynaptic boutons required for classical conditioning 2011
2009 Cleavage of proBDNF to BDNF by a tolloid-like metalloproteinase is required for acquisition of in vitro eyeblink classical conditioning 2009
2009 BDNF-induced synaptic delivery of AMPAR subunits is differentially dependent on NMDA receptors and requires ERK.  Neurobiology of Learning and Memory.  91:243-249. 2009
2008 Coordinate action of pre- and postsynaptic brain-derived neurotrophic factor is required for AMPAR trafficking and acquisition of in vitro classical conditioning.  Neuroscience.  155:686-697. 2008

Principal Investigator On

Investigator On

Education And Training

  • Doctor of Philosophy in Biomedical Sciences, University of South Dakota 2010

    • Full Name

  • Wei Li