Biographical Sketch
The goal of the lab is to halt the progression of synucleinopathies including Parkinson's Disease, and Lewy Body Dementia, the second most common cognitive disorder after Alzheimer's Disease. The lab uses mouse models to determine the role of genes implicated in these neurodegenerative diseases on formation of alpha-synuclein inclusions. We also want to determine how these aggregates cause defects in neuron function, as well as motor and cognitive phenotypes. Techniques used in the lab range from super-resolution microscopy in mouse and human brain tissues, live cell imaging, protein purification and biochemistry, and behavior. Dr. Volpicelli-Daley is also dedicated to ensuring the success of future scientists and physicians.