Positions

Selected Publications

Academic Article

Year Title Altmetric
2022 Scleral crosslinking using genipin can compromise retinal structure and function in tree shrewsExperimental Eye Research.  219. 2022
2022 Cone Photoreceptor Loss in Light-Damaged Albino RatsInternational Journal of Molecular Sciences.  23. 2022
2022 ERG and Behavioral CFF in Light-Damaged Albino RatsInternational Journal of Molecular Sciences.  23. 2022
2020 Selective Ablation of Dehydrodolichyl Diphosphate Synthase in Murine Retinal Pigment Epithelium (RPE) Causes RPE Atrophy and Retinal DegenerationCells.  9. 2020
2020 A quantitative account of mammalian rod phototransduction with PDE6 dimeric activation: Responses to bright flashesOpen Biology.  10. 2020
2019 Phototransduction gain at the G-protein, transducin, and effector protein, phosphodiesterase-6, stages in retinal rods 2019
2018 Implications of dimeric activation of PDE6 for rod phototransductionOpen Biology.  8. 2018
2018 Optimizing ERG measures of scotopic and photopic critical flicker frequencyAdvances in Experimental Medicine and Biology.  1074:145-150. 2018
2017 Glycogen synthase kinase 3 regulates photic signaling in the suprachiasmatic nucleusEuropean Journal of Neuroscience.  45:1102-1110. 2017
2016 Quantitative modeling of the molecular steps underlying shut-off of rhodopsin activity in rod phototransductionMolecular Vision.  22:674-696. 2016
2016 Signalling beyond photon absorption: Extracellular retinoids and growth factors modulate rod photoreceptor sensitivity 2016
2015 Increased visual sensitivity following periods of dim illumination 2015
2014 Hippocampal and cortical primary cilia are required for aversive memory in micePLoS One.  9. 2014
2014 Transient knockdown of SULT4A1 induces upregulation of phototransduction proteins 2014
2014 Adaptive potentiation in rod photoreceptors after light exposureJournal of General Physiology.  143:733-743. 2014
2014 Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLDJournal of Experimental Medicine.  211:1937-1945. 2014
2014 Inhibition of sult4a1 expression induces up-regulation of phototransduction gene expression in 72-hour postfertilization zebrafish larvaeDrug Metabolism and Disposition.  42:947-953. 2014
2014 Overexpression of rod photoreceptor glutamic acid rich protein 2 (GARP2) increases gain and slows recovery in mouse retinaCell Communication and Signaling.  12. 2014
2013 The age-regulating protein klotho is vital to sustain retinal function 2013
2012 Age-related changes in Cngb1-X1 knockout mice: Prolonged cone survivalDocumenta Ophthalmologica.  124:163-175. 2012
2012 Comparative intrinsic optical signal imaging of wild-type and mutant mouse retinasOptics Express.  20:7646-7654. 2012
2012 ERG critical flicker frequency assessment in humansAdvances in Experimental Medicine and Biology.  723:503-509. 2012
2012 Measuring rodent electroretinograms to assess retinal functionMethods in Molecular Biology.  884:265-276. 2012
2012 Measuring rodent electroretinograms to assess retinal functionMethods in Molecular Biology.  884:265-276. 2012
2010 1 rhodopsin mutations in congenital night blindnessAdvances in Experimental Medicine and Biology.  664:263-272. 2010
2010 Combined optical coherence tomography and electroretinography system for in vivo simultaneous morphological and functional imaging of the rodent retinaJournal of Biomedical Optics.  15. 2010
2009 Knockout of GARPs and the β-subunit of the rod cGMP-gated channel disrupts disk morphogenesis and rod outer segment structural integrityJournal of Cell Science.  122:1192-1200. 2009
2008 Human oscillatory potentials: Intensity-dependence of timing and amplitudeDocumenta Ophthalmologica.  117:215-222. 2008
2007 Flicker assessment of rod and cone function in a model of retinal degenerationDocumenta Ophthalmologica.  115:165-172. 2007
2005 Altered light responses of single rod photoreceptors in transgenic pigs expressing P347L or P347S rhodopsinMolecular Vision.  11:1246-1256. 2005
2005 Acute aminoglycoside retinal toxicity in vivo and in vitro 2005
2005 Blockade of amiloride-sensitive sodium channels alters multiple components of the mammalian electroretinogramVisual Neuroscience.  22:143-151. 2005
2004 Oscillatory potential analysis and ERGs of normal and diabetic rats 2004
2003 GTPase regulators and photoresponses in cones of the eastern chipmunk 2003
2001 Growth factors regulate phototransduction in retinal rods by modulating cyclic nucleotide-gated channels through dephosphorylation of a specific tyrosine residue 2001
1998 Spectra of human L conesVision Research.  38:3663-3670. 1998
1998 Expression of L cone pigment gene subtypes in femalesVision Research.  38:3221-3225. 1998
1998 Aberrant photon responses in rods of the macaque monkeyVisual Neuroscience.  15:153-159. 1998
1998 Rod outer segment maintenance is enhanced in the presence of BFGF, CNTF and GDNFExperimental Eye Research.  66:791-805. 1998
1998 The cloning of GRK7, a candidate cone opsin kinase, from cone- and rod-dominant mammalian retinas.Molecular Vision.  4:27. 1998
1996 Enhanced survival of mammalian rod photoreceptors in cultures 1996
1994 PHOTOTRANSDUCTION IN PRIMATE PHOTORECEPTORS 1994
1993 Visual transduction in human rod photoreceptors. 1993
1990 Effects of modified chromophores on the spectral sensitivity of salamander, squirrel and macaque cones. 1990
1990 Cone excitations and color vision 1990
1989 Transduction in primate conesNeuroscience research. Supplement : the official journal of the Japan Neuroscience Society.  10. 1989
1988 Photocurrents of cone photoreceptors of the golden‐mantled ground squirrel. 1988
1988 Spectral sensitivity of primate photoreceptorsVisual Neuroscience.  1:255-261. 1988
1987 Spectral sensitivity of human cone photoreceptorsNature.  325:439-441. 1987
1986 Functional properties of twin and single conesNeuroscience Research.  4. 1986
1986 Telodendrites of cone photoreceptors: Structure and probable functionJournal of Comparative Neurology.  249:13-27. 1986
1979 Intraretinal distribution of cone pigments in certain teleost fishesScience.  204:523-526. 1979

Teaching Activities

  • VIS746 - Retina and Subcortical Systems (Spring Term 2008)
  • VIS746 - Retina and Subcortical Systems (Spring Term 2009)
  • VIS746 - Retina and Subcortical Systems (Spring Term 2010)
  • VIS746 - Retina and Subcortical Systems (Spring Term 2011)
  • VIS746 - Retina and Subcortical Systems (Spring Term 2012)
  • VS111 - Ocular Anatomy (Fall Term 2008)
  • VS111 - Ocular Anatomy (Fall Term 2009)
  • VS111 - Ocular Anatomy (Fall Term 2010)
  • VS111 - Ocular Anatomy (Fall Term 2011)
  • VS111 - Ocular Anatomy (Fall Term 2012)
  • VS111 - Ocular Anatomy (Fall Term 2013)
  • VS111 - Ocular Anatomy (Fall Term 2014)
  • VS111 - Ocular Anatomy (Fall Term 2015)
  • VS111 - Ocular Anatomy (Fall Term 2016)
  • VS111 - Ocular Anatomy (Fall Term 2017)
  • VS111 - Ocular Anatomy (Fall Term 2018)
  • VS111 - Ocular Anatomy (Fall Term 2019)
  • VS111 - Ocular Anatomy (Fall Term 2020)
  • VS111 - Ocular Anatomy (Fall Term 2021)
  • VS111 - Ocular Anatomy (Fall Term 2022)
  • VS111 - Ocular Anatomy (Summer Term 2017)
  • VS111L - Ocular Anatomy Lab (Fall Term 2008)
  • VS111L - Ocular Anatomy Lab (Fall Term 2008)
  • VS111L - Ocular Anatomy Lab (Fall Term 2009)
  • VS111L - Ocular Anatomy Lab (Fall Term 2009)
  • VS111L - Ocular Anatomy Lab (Fall Term 2010)
  • VS111L - Ocular Anatomy Lab (Fall Term 2010)
  • VS111L - Ocular Anatomy Lab (Fall Term 2011)
  • VS111L - Ocular Anatomy Lab (Fall Term 2011)
  • VS111L - Ocular Anatomy Lab (Fall Term 2012)
  • VS111L - Ocular Anatomy Lab (Fall Term 2012)
  • VS111L - Ocular Anatomy Lab (Fall Term 2013)
  • VS111L - Ocular Anatomy Lab (Fall Term 2013)
  • VS111L - Ocular Anatomy Lab (Fall Term 2014)
  • VS111L - Ocular Anatomy Lab (Fall Term 2015)
  • VS111L - Ocular Anatomy Lab (Fall Term 2016)
  • VS111L - Ocular Anatomy Lab (Fall Term 2017)
  • VS111L - Ocular Anatomy Lab (Fall Term 2018)
  • VS111L - Ocular Anatomy Lab (Fall Term 2019)
  • VS111L - Ocular Anatomy Lab (Fall Term 2020)
  • VS111L - Ocular Anatomy Lab (Fall Term 2021)
  • VS111L - Ocular Anatomy Lab (Fall Term 2022)
  • VS112 - Ocular Anatomy (Fall Term 2007)
  • Education And Training

  • Doctor of Philosophy in Physiology, University of Minnesota System : Twin Cities 1985
  • Full Name

  • Timothy Kraft