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Timothy Kraft
Professor / Associate Dean
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E-mail
twkraft@uab.edu
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Timothy Kraft
Professor / Associate Dean
Positions
Scientist (C)
,
Comprehensive Neuroscience Center
,
General Clinical Research Center
Scientist (C)
,
Center for Biophysical Sciences and Engineering (CBSE)
,
School of Optometry
Professor (P)
,
Dept of Optometry & Vision Science
,
School of Optometry
Associate Dean of Research
,
Dept of Optometry & Vision Science
,
School of Optometry
Associate Dean for Research and Graduate Studies
,
Dept of Optometry & Vision Science
,
School of Optometry
Scientist (C)
,
Vision Science Research Center
,
Dept of Optometry & Vision Science
Scientist (C)
,
Civitan International Research Center
,
Academic Joint Departments
Associate Professor (S)
,
Neurobiology
,
Academic Joint Departments
Publications
Research
Teaching
Background
Contact
Publications
Selected Publications
Academic Article
Filter
Year
Title
Altmetric
2022
Scleral crosslinking using genipin can compromise retinal structure and function in tree shrews
.
Experimental Eye Research
. 219.
2022
2022
Cone Photoreceptor Loss in Light-Damaged Albino Rats
.
International Journal of Molecular Sciences
. 23.
2022
2022
ERG and Behavioral CFF in Light-Damaged Albino Rats
.
International Journal of Molecular Sciences
. 23.
2022
2020
Selective Ablation of Dehydrodolichyl Diphosphate Synthase in Murine Retinal Pigment Epithelium (RPE) Causes RPE Atrophy and Retinal Degeneration
.
Cells
. 9.
2020
2020
A quantitative account of mammalian rod phototransduction with PDE6 dimeric activation: Responses to bright flashes
.
Open Biology
. 10.
2020
2019
Phototransduction gain at the G-protein, transducin, and effector protein, phosphodiesterase-6, stages in retinal rods
2019
2018
Implications of dimeric activation of PDE6 for rod phototransduction
.
Open Biology
. 8.
2018
2018
Optimizing ERG measures of scotopic and photopic critical flicker frequency
.
Advances in Experimental Medicine and Biology
. 1074:145-150.
2018
2017
Glycogen synthase kinase 3 regulates photic signaling in the suprachiasmatic nucleus
.
European Journal of Neuroscience
. 45:1102-1110.
2017
2016
Quantitative modeling of the molecular steps underlying shut-off of rhodopsin activity in rod phototransduction
.
Molecular Vision
. 22:674-696.
2016
2016
Signalling beyond photon absorption: Extracellular retinoids and growth factors modulate rod photoreceptor sensitivity
2016
2015
Increased visual sensitivity following periods of dim illumination
2015
2014
Hippocampal and cortical primary cilia are required for aversive memory in mice
.
PLoS One
. 9.
2014
2014
Transient knockdown of SULT4A1 induces upregulation of phototransduction proteins
2014
2014
Adaptive potentiation in rod photoreceptors after light exposure
.
Journal of General Physiology
. 143:733-743.
2014
2014
Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD
.
Journal of Experimental Medicine
. 211:1937-1945.
2014
2014
Inhibition of sult4a1 expression induces up-regulation of phototransduction gene expression in 72-hour postfertilization zebrafish larvae
.
Drug Metabolism and Disposition
. 42:947-953.
2014
2014
Overexpression of rod photoreceptor glutamic acid rich protein 2 (GARP2) increases gain and slows recovery in mouse retina
.
Cell Communication and Signaling
. 12.
2014
2013
The age-regulating protein klotho is vital to sustain retinal function
2013
2012
Age-related changes in Cngb1-X1 knockout mice: Prolonged cone survival
.
Documenta Ophthalmologica
. 124:163-175.
2012
2012
Comparative intrinsic optical signal imaging of wild-type and mutant mouse retinas
.
Optics Express
. 20:7646-7654.
2012
2012
ERG critical flicker frequency assessment in humans
.
Advances in Experimental Medicine and Biology
. 723:503-509.
2012
2012
Measuring rodent electroretinograms to assess retinal function
.
Methods in Molecular Biology
. 884:265-276.
2012
2012
Measuring rodent electroretinograms to assess retinal function
.
Methods in Molecular Biology
. 884:265-276.
2012
2010
1 rhodopsin mutations in congenital night blindness
.
Advances in Experimental Medicine and Biology
. 664:263-272.
2010
2010
Combined optical coherence tomography and electroretinography system for in vivo simultaneous morphological and functional imaging of the rodent retina
.
Journal of Biomedical Optics
. 15.
2010
2009
Knockout of GARPs and the β-subunit of the rod cGMP-gated channel disrupts disk morphogenesis and rod outer segment structural integrity
.
Journal of Cell Science
. 122:1192-1200.
2009
2008
Human oscillatory potentials: Intensity-dependence of timing and amplitude
.
Documenta Ophthalmologica
. 117:215-222.
2008
2007
Flicker assessment of rod and cone function in a model of retinal degeneration
.
Documenta Ophthalmologica
. 115:165-172.
2007
2005
Altered light responses of single rod photoreceptors in transgenic pigs expressing P347L or P347S rhodopsin
.
Molecular Vision
. 11:1246-1256.
2005
2005
Acute aminoglycoside retinal toxicity in vivo and in vitro
2005
2005
Blockade of amiloride-sensitive sodium channels alters multiple components of the mammalian electroretinogram
.
Visual Neuroscience
. 22:143-151.
2005
2004
Oscillatory potential analysis and ERGs of normal and diabetic rats
2004
2003
GTPase regulators and photoresponses in cones of the eastern chipmunk
2003
2001
Growth factors regulate phototransduction in retinal rods by modulating cyclic nucleotide-gated channels through dephosphorylation of a specific tyrosine residue
2001
1998
Spectra of human L cones
.
Vision Research
. 38:3663-3670.
1998
1998
Expression of L cone pigment gene subtypes in females
.
Vision Research
. 38:3221-3225.
1998
1998
Aberrant photon responses in rods of the macaque monkey
.
Visual Neuroscience
. 15:153-159.
1998
1998
Rod outer segment maintenance is enhanced in the presence of BFGF, CNTF and GDNF
.
Experimental Eye Research
. 66:791-805.
1998
1998
The cloning of GRK7, a candidate cone opsin kinase, from cone- and rod-dominant mammalian retinas.
.
Molecular Vision
. 4:27.
1998
1996
Enhanced survival of mammalian rod photoreceptors in cultures
1996
1994
PHOTOTRANSDUCTION IN PRIMATE PHOTORECEPTORS
1994
1993
Visual transduction in human rod photoreceptors.
1993
1990
Effects of modified chromophores on the spectral sensitivity of salamander, squirrel and macaque cones.
1990
1990
Cone excitations and color vision
1990
1989
Transduction in primate cones
.
Neuroscience research. Supplement : the official journal of the Japan Neuroscience Society
. 10.
1989
1988
Photocurrents of cone photoreceptors of the golden‐mantled ground squirrel.
1988
1988
Spectral sensitivity of primate photoreceptors
.
Visual Neuroscience
. 1:255-261.
1988
1987
Spectral sensitivity of human cone photoreceptors
.
Nature
. 325:439-441.
1987
1986
Functional properties of twin and single cones
.
Neuroscience Research
. 4.
1986
1986
Telodendrites of cone photoreceptors: Structure and probable function
.
Journal of Comparative Neurology
. 249:13-27.
1986
1979
Intraretinal distribution of cone pigments in certain teleost fishes
.
Science
. 204:523-526.
1979
Research
Principal Investigator On
Absolute Sensitivity of Mammalian Cones
awarded by
Johns Hopkins University
Comprehensive Quantification of Cone Dynamics
awarded by
National Eye Institute/NIH/DHHS
Short Term Adaptations in Photoreceptors
awarded by
National Eye Institute/NIH/DHHS
UAB Core Grant for Vision Research - Ocular Phenotyping Core
awarded by
National Eye Institute/NIH/DHHS
UAB Vision Science Research Center - OcPheno Core
awarded by
National Eye Institute/NIH/DHHS
UAB Vision Science Research Center - OcPheno Core
awarded by
National Eye Institute/NIH/DHHS
Investigator On
Analysis of Retina Rod Photoreceptor GARP and cGMP-Gated Cation Channel
awarded by
National Eye Institute/NIH/DHHS
Analysis of Retina Rod Photoreceptor GARP and cGMP-Gated Channel
awarded by
National Eye Institute/NIH/DHHS
Functional Imaging of Retinal Photoreceptors
awarded by
National Eye Institute/NIH/DHHS
SULT4A1 in Zebrafish Development
awarded by
National Institute of General Medical Sciences/NIH/DHHS
Scleral Remodeling in Myopia
awarded by
National Eye Institute/NIH/DHHS
UAB Core Grant for Vision Research
awarded by
National Eye Institute/NIH/DHHS
UAB Vision Science Research Center
awarded by
National Eye Institute/NIH/DHHS
UAB Vision Science Research Center
awarded by
National Eye Institute/NIH/DHHS
Teaching
Teaching Activities
VIS746 - Retina and Subcortical Systems (Spring Term 2008)
VIS746 - Retina and Subcortical Systems (Spring Term 2009)
VIS746 - Retina and Subcortical Systems (Spring Term 2010)
VIS746 - Retina and Subcortical Systems (Spring Term 2011)
VIS746 - Retina and Subcortical Systems (Spring Term 2012)
VS111 - Ocular Anatomy (Fall Term 2008)
VS111 - Ocular Anatomy (Fall Term 2009)
VS111 - Ocular Anatomy (Fall Term 2010)
VS111 - Ocular Anatomy (Fall Term 2011)
VS111 - Ocular Anatomy (Fall Term 2012)
VS111 - Ocular Anatomy (Fall Term 2013)
VS111 - Ocular Anatomy (Fall Term 2014)
VS111 - Ocular Anatomy (Fall Term 2015)
VS111 - Ocular Anatomy (Fall Term 2016)
VS111 - Ocular Anatomy (Fall Term 2017)
VS111 - Ocular Anatomy (Fall Term 2018)
VS111 - Ocular Anatomy (Fall Term 2019)
VS111 - Ocular Anatomy (Fall Term 2020)
VS111 - Ocular Anatomy (Fall Term 2021)
VS111 - Ocular Anatomy (Fall Term 2022)
VS111 - Ocular Anatomy (Summer Term 2017)
VS111L - Ocular Anatomy Lab (Fall Term 2008)
VS111L - Ocular Anatomy Lab (Fall Term 2008)
VS111L - Ocular Anatomy Lab (Fall Term 2009)
VS111L - Ocular Anatomy Lab (Fall Term 2009)
VS111L - Ocular Anatomy Lab (Fall Term 2010)
VS111L - Ocular Anatomy Lab (Fall Term 2010)
VS111L - Ocular Anatomy Lab (Fall Term 2011)
VS111L - Ocular Anatomy Lab (Fall Term 2011)
VS111L - Ocular Anatomy Lab (Fall Term 2012)
VS111L - Ocular Anatomy Lab (Fall Term 2012)
VS111L - Ocular Anatomy Lab (Fall Term 2013)
VS111L - Ocular Anatomy Lab (Fall Term 2013)
VS111L - Ocular Anatomy Lab (Fall Term 2014)
VS111L - Ocular Anatomy Lab (Fall Term 2015)
VS111L - Ocular Anatomy Lab (Fall Term 2016)
VS111L - Ocular Anatomy Lab (Fall Term 2017)
VS111L - Ocular Anatomy Lab (Fall Term 2018)
VS111L - Ocular Anatomy Lab (Fall Term 2019)
VS111L - Ocular Anatomy Lab (Fall Term 2020)
VS111L - Ocular Anatomy Lab (Fall Term 2021)
VS111L - Ocular Anatomy Lab (Fall Term 2022)
VS112 - Ocular Anatomy (Fall Term 2007)
Background
Education And Training
Doctor of Philosophy in Physiology,
University of Minnesota System : Twin Cities
1985
Contact
Full Name
Timothy
Kraft