The Metabolic Basic of Kidney Cancer - Our laboratory’s principal focus has been to study the metabolic alterations of kidney cancer, also referred to as renal cell carcinoma (RCC). We study both rare hereditary forms of RCC as well as in sporadic kidney cancer. We are interested in hereditary forms of renal cancer as we believe the study of these disease variants can provide insight into more common, sporadic forms of this disease. We are interested in how metabolic remodeling contributes to tumor formation, progression, as well as response to therapy. In particular, our laboratory is interested in the connection between tumor metabolism and epigenetics. The overarching goal is to perform mechanistic studies that will advance our current knowledge base of kidney cancer in order to develop better methods to treat patients with advanced disease.
Keywords - urologic oncology, scientific research understanding the molecular basis of renal cancer
