Shah S. Hussain received his MS degree from Jamia Millia Islamia University in 2009, with a specialization in Bioscience, and his MPhil degree from the University of Delhi in 2011. He completed his Ph.D. (Doctor of Philosophy) at the University of Delhi in 2017 while studying the protein chemistry of active (in vitro and in vivo) recombinant glycoengineered hormones and he was trained in molecular biology at the Indian Institute of Sciences, Bangalore (IISc), India.
In 2017 during his first postdoctoral training at the Department of Immunology, Florida International University, Miami, involved studying the role of Long Noncoding RNA in Allergic Asthma Associated Hyperreactive Response of Airway Epithelial Cells. Dr. Hussain pursued his interest in the field of Respiratory Biology and joined as the Postdoc fellow in Dr. Rowe’s lab, in the Department of Medicine and CFRC center at the University of Alabama at Birmingham, USA. From his postdoctoral work, he has published his work in multiple prestigious journals, including, Nature, JCI, ERJ, and MucosalImmunology
In 2022, Dr. Hussain was appointed as an Instructor in the UAB Department of Medicine (Pulmonary, Allergy, and Critical Care Medicine). Dr. Hussain is passionate about small airway disease and the role of abnormal mucus in lung diseases including chronic obstructive pulmonary disease, Alpha-1-antitrypsin deficiency, idiopathic pulmonary fibrosis, and Cystic fibrosis. Dr. Hussain’s research interests are grounded in the study of respiratory infectious diseases like SARS-COV-2, and HIV, cutting-edge discovery in airway disease biology and ciliary dynamics, and translational research in IPF, CF, Alpha-1-Antitrypsin COPD, and other airway diseases.
In Dr. Hussain’s professional engagement at UAB thus far, he has developed a novel technique that enables micro-CT imaging of the microstructure of the smallest airways (less than 2mm) in ferret lungs, paving the path for a new understanding of progressive airway diseases with small airways involvement including COPD, CF, and IPF. Using this novel method, he has been focusing on understanding the complex pathological changes in small airway disease progression, including novel aspects of disease mechanism that heretofore have been repeatedly documented in human specimens, but for which mechanistic understanding has been lacking.