Positions

Selected Publications

Academic Article

Year Title Altmetric
2022 Pulmonary surfactant protein B carried by HDL predicts incident CVD in patients with type 1 diabetesJournal of Lipid Research.  64. 2022
2022 Conformational flexibility of apolipoprotein A-I amino- and carboxy-termini is necessary for lipid binding but not cholesterol effluxJournal of Lipid Research.  63. 2022
2022 The regulatory domains of the lipid exporter ABCA1 form domain swapped latchesPLoS One.  17. 2022
2021 Apolipoprotein A-I modulates HDL particle size in the absence of apolipoprotein A-IIJournal of Lipid Research.  62. 2021
2021 Erratum: Glutamine-451 confers sensitivity to oxidative inhibition and heme-thiolate sulfenylation of cytochrome P450 4B1 (Chemical Research in Toxicology (2019) 32:3 (484-492) DOI: 10.1021/acs.chemrestox.8b00353)Chemical Research in Toxicology.  34:930. 2021
2020 Diabetes Impairs Cellular Cholesterol Efflux from ABCA1 to Small HDL ParticlesCirculation Research.  127:1198-1210. 2020
2019 Apolipoprotein A1 Forms 5/5 and 5/4 Antiparallel Dimers in Human High-density LipoproteinMolecular and Cellular Proteomics.  18:854-864. 2019
2019 Glutamine-451 Confers Sensitivity to Oxidative Inhibition and Heme-Thiolate Sulfenylation of Cytochrome P450 4B1Chemical Research in Toxicology.  32:484-492. 2019
2018 Tertiary structure of apolipoprotein A-I in nascent high-density lipoproteinsProceedings of the National Academy of Sciences of USA.  115:5163-5168. 2018
2018 A thumbwheel mechanism for APOA1 activation of LCAT activity in HDLJournal of Lipid Research.  59:1244-1255. 2018
2017 Relationship between Amphipathic β Structures in the β1 Domain of Apolipoprotein B and the Properties of the Secreted Lipoprotein Particles in McA-RH7777 CellsBiochemistry.  56:4084-4094. 2017
2017 A consensus model of human apolipoprotein A-I in its monomeric and lipid-free stateNature Structural and Molecular Biology.  24:1093-1099. 2017
2016 Computational studies of plasma lipoprotein lipidsBBA: Biomembranes.  1858:2401-2420. 2016
2016 An evaluation of the crystal structure of c-terminal truncated apolipoprotein A-I in solution reveals structural dynamics related to lipid bindingJournal of Biological Chemistry.  291:5439-5451. 2016
2015 Surface Density-Induced Pleating of a Lipid Monolayer Drives Nascent High-Density Lipoprotein AssemblyStructure.  23:1214-1226. 2015
2015 A robust all-atom model for LCAT generated by homology modelingJournal of Lipid Research.  56:620-634. 2015
2014 An experimentally robust model of monomeric apolipoprotein A-I created from a chimera of two x-ray structures and molecular dynamics simulationsBiochemistry.  53:7625-7640. 2014
2014 The structure of human apolipoprotein A-IV as revealed by stable isotope-assisted cross-linking, molecular dynamics, and small angle X-ray scatteringJournal of Biological Chemistry.  289:5596-5608. 2014
2013 Structural basis for distinct functions of the naturally occurring cys mutants of human apolipoprotein A-IJournal of Lipid Research.  54:3244-3257. 2013
2013 MD simulations suggest important surface differences between reconstituted and circulating spherical HDLJournal of Lipid Research.  54:2718-2732. 2013
2013 Volumetric determination of apolipoprotein stoichiometry of circulating HDL subspeciesJournal of Lipid Research.  54:2733-2744. 2013
2013 Helical domains that mediate lipid solubilization and ABCA1-specific cholesterol efflux in apolipoproteins C-I and A-IIJournal of Lipid Research.  54:1939-1948. 2013
2012 Validation of previous computer models and MD simulations of discoidal HDL by a recent crystal structure of apoA-IJournal of Lipid Research.  53:1851-1863. 2012
2012 Sidedness of interfacial arginine residues and anti-atherogenicity of apolipoprotein A-I mimetic peptidesJournal of Lipid Research.  53:849-858. 2012
2012 Rotational and hinge dynamics of discoidal high density lipoproteins probed by interchain disulfide bond formationBBA: Molecular and Cell Biology of Lipids.  1821:481-489. 2012
2011 "Sticky" and "promiscuous", the yin and yang of apolipoprotein A-I termini in discoidal high-density lipoproteins: A combined computational-experimental approachBiochemistry.  50:2249-2263. 2011
2011 Sequence conservation of apolipoprotein A-I affords novel insights into HDL structure-functionJournal of Lipid Research.  52:435-450. 2011
2010 Assessment of the validity of the double superhelix model for reconstituted high density lipoproteins: A combined computational-experimental approachJournal of Biological Chemistry.  285:41161-41171. 2010
2010 Structures of discoidal high density lipoproteins: A combined computational-experimental approachJournal of Biological Chemistry.  285:4652-4665. 2010
2009 Dynamics of activation of lecithin:cholesterol acyltransferase by apolipoprotein A-IBiochemistry.  48:11196-11210. 2009
2009 Thermal stability of apolipoprotein A-I in high-density lipoproteins by molecular dynamicsBiophysical Journal.  96:354-371. 2009
2008 Effect of leucine to phenylalanine substitution on the nonpolar face of a class A amphipathic helical peptide on its interaction with lipid: High resolution solution NMR studies of 4F-dimyristoylphosphatidylcholine discoidal complexJournal of Biological Chemistry.  283:34393-34402. 2008
2008 Charged amino acid residues 997-1000 of human apolipoprotein B100 are critical for the initiation of lipoprotein assembly and the formation of a stable lipidated primordial particle in McA-RH7777 cellsJournal of Biological Chemistry.  283:29251-29265. 2008
2008 Structure of spheroidal HDL particles revealed by combined atomistic and coarse-grained simulations (Biophysical Journal (2008) 94,6 (2306-2319))Biophysical Journal.  94:3361. 2008
2008 Structure of spheroidal HDL particles revealed by combined atomistic and coarse-grained simulationsBiophysical Journal.  94:2306-2319. 2008
2008 The Editor's Roundtable: Expanded Versus Standard Lipid Panels in Assessing and Managing Cardiovascular RiskAmerican Journal of Cardiology.  101:828-842. 2008
2007 Microsomal triglyceride transfer protein activity is not required for the initiation of apolipoprotein B-containing lipoprotein assembly in McA-RH7777 cellsJournal of Biological Chemistry.  282:28597-28608. 2007
2007 Structural requirements for antioxidative and anti-inflammatory properties of apolipoprotein A-I mimetic peptidesJournal of Lipid Research.  48:1915-1923. 2007
2006 Synthetic peptides: Managing lipid disordersCurrent Opinion in Lipidology.  17:233-237. 2006
2006 Association of a model class A (apolipoprotein) amphipathic α helical peptide with lipid: High resolution NMR studies of peptide-lipid discoidal complexesJournal of Biological Chemistry.  281:6511-6519. 2006
2006 Novel changes in discoidal high density lipoprotein morphology: A molecular dynamics studyBiophysical Journal.  90:4345-4360. 2006
2005 A mass spectrometric determination of the conformation of dimeric apolipoprotein A-I in discoidal high density lipoproteinsBiochemistry.  44:8600-8607. 2005
2005 Assembly of lipoprotein particles containing apolipoprotein-B: Structural model for the nascent lipoprotein particleBiophysical Journal.  88:2789-2800. 2005
2004 Double belt structure of discoidal high density lipoproteins: Molecular basis for size heterogeneityJournal of Molecular Biology.  343:1293-1311. 2004
2004 Apolipoprotein B-containing lipoprotein particle assembly. Lipid capacity of the nascent lipoprotein particleJournal of Biological Chemistry.  279:39757-39766. 2004
2004 Aromatic residue position on the nonpolar face of class A amphipathic helical peptides determines biological activityJournal of Biological Chemistry.  279:26509-26517. 2004
2004 An Apolipoprotein AI Mimetic Peptide: Membrane Interactions and the Role of CholesterolBiochemistry.  43:5073-5083. 2004
2003 Human apolipoprotein AI mimetic peptides for the treatment of atherosclerosisCurrent Opinion in Investigational Drugs.  4:1100-1104. 2003
2002 Comparative models for human apolipoprotein A-I bound to lipid in discoidal high-density lipoprotein particlestBiochemistry.  41:10895-10905. 2002
2002 Identification of the proteoglycan binding site in apolipoprotein B48Journal of Biological Chemistry.  277:32228-32233. 2002
2002 The N-terminal 1000 residues of apolipoprotein B associate with microsomal triglyceride transfer protein to create a lipid transfer pocket required for lipoprotein assemblyBiochemistry.  41:6978-6987. 2002
2002 Molecular dynamics simulations on discoidal HDL particles suggest a mechanism for rotation in the apo A-I belt modelJournal of Molecular Biology.  324:703-721. 2002
2002 The role of non-LDL:non-HDL particles in atherosclerosis.Current Diabetes Reports.  2:282-288. 2002
2001 Distribution and correlates of lipoproteins and their subclasses in black and white young adults. The Bogalusa Heart StudyAtherosclerosis.  159:391-397. 2001
2001 Structure of apolipoprotein B-100 in low density lipoproteinsJournal of Lipid Research.  42:1346-1367. 2001
2001 Effects of increasing hydrophobicity on the physical-chemical and biological properties of a class A amphipathic helical peptideJournal of Lipid Research.  42:1096-1104. 2001
2001 A new synthetic class A amphipathic peptide analogue protects mice from diet-induced atherosclerosisJournal of Lipid Research.  42:545-552. 2001
2001 Solution NMR structure of a model class A (apolipoprotein) amphipathic α helical peptidePeptides.  22:567-573. 2001
2001 Insulin resistance, dietary cholesterol, and cholesterol concentration in postmenopausal womenMetabolism: clinical and experimental.  50:594-597. 2001
2001 Osmotically induced membrane tension modulates membrane permeabilization by class L amphipathic helical peptides: Nucleation model of defect formationBiophysical Journal.  81:949-959. 2001
2000 Detailed molecular model of apolipoprotein A-I on the surface of high-density lipoproteins and its functional implicationsTrends in Cardiovascular Medicine.  10:246-252. 2000
2000 Structure and function of apolipoprotein A-I and high-density lipoproteinCurrent Opinion in Lipidology.  11:105-115. 2000
2000 Molecular belt models for the apolipoprotein A-I Paris and milano mutationsBiophysical Journal.  79:1679-1685. 2000
1999 A detailed molecular belt model for apolipoprotein A-I in discoidal high density lipoproteinJournal of Biological Chemistry.  274:31755-31758. 1999
1999 N-terminal domain of apolipoprotein B has structural homology to lipovitellin and microsomal triglyceride transfer protein: A 'lipid pocket' model for self-assembly of apoB-containing lipoprotein particlesJournal of Lipid Research.  40:1401-1416. 1999
1999 An amphipathic α-helix at a membrane interface: A structural study using a novel X-ray diffraction methodJournal of Molecular Biology.  290:99-117. 1999
1999 Apolipoprotein-mediated plasma membrane microsolubilization: Role of lipid affinity and membrane penetration in the efflux of cellular cholesterol and phospholipidJournal of Biological Chemistry.  274:2021-2028. 1999
1999 Increased prevalence of smaller and denser LDL particles in Asian IndiansArteriosclerosis, Thrombosis and Vascular Biology.  19:2749-2755. 1999
1999 Perilipins, ADRP, and other proteins that associate with intracellular neutral lipid droplets in animal cellsSeminars in Cell and Developmental Biology.  10:51-58. 1999
1998 In vitro production of β-very low density lipoproteins and small, dense low density lipoproteins in mildly hypertriglyceridemic plasma: Role of activities of lecithin:cholester acyltransferase, cholesterylester transfer proteins and lipoprotein lipaseAtherosclerosis.  141:209-225. 1998
1998 Studies of synthetic peptides of human apolipoprotein A-I containing tandem amphipathic α-helixesBiochemistry.  37:10313-10324. 1998
1998 Studies of kinetics and equilibrium membrane binding of class A and class L model amphipathic peptidesBBA: Biomembranes.  1368:343-354. 1998
1998 Apolipoprotein B-100: Conservation of lipid-associating amphipathic secondary structural motifs in nine species of vertebratesJournal of Lipid Research.  39:85-102. 1998
1998 Models for the longitudinal genetic analysis of same-age twins: Application to HDL cholesterolTwin Research and Human Genetics.  1:3-8. 1998
1998 Potencies of lipoproteins in fasting and postprandial plasma to accept additional cholesterol molecules released from cell membranesArteriosclerosis, Thrombosis and Vascular Biology.  18:1217-1230. 1998
1997 Quantification of HDL2 and HDL3 cholesterol by the vertical auto profile-II (VAP-II) methodologyJournal of Lipid Research.  38:2353-2364. 1997
1997 Effect of vesicle size on their interaction with class A amphipathic helical peptidesJournal of Lipid Research.  38:2147-2154. 1997
1997 Interaction of class A amphipathic helical peptides with phospholipid unilamellar vesiclesJournal of Lipid Research.  38:2134-2146. 1997
1997 Transgenic mice expressing human ApoB95 and ApoB97. Evidence that sequences within the carboxyl-terminal portion of human apoB100 are important for the assembly of lipoprotein(a)Journal of Biological Chemistry.  272:23616-23622. 1997
1997 Role of lipids in the permeabilization of membranes by class L amphipathic helical peptidesBiochemistry.  36:9237-9245. 1997
1996 Probing structure and function of VLDL by synthetic amphipathic helical peptidesJournal of Lipid Research.  37:1099-1112. 1996
1996 Only the two end helixes of eight tandem amphipathic helical domains of human Apo A-I have significant lipid affinity: Implications for HDL assemblyArteriosclerosis, Thrombosis and Vascular Biology.  16:328-338. 1996
1995 Molecular Basis for Prokaryotic Specificity of Magainin-Induced LysisBiochemistry.  34:4393-4401. 1995
1995 Identification and characterization of a new human gene (APOC4) in the apolipoprotein E, C-I, and C-II gene locusGenomics.  28:291-300. 1995
1995 A prospective, randomized trial of phenytoin in nonepileptic subjects with reduced HDL cholesterolArteriosclerosis, Thrombosis and Vascular Biology.  15:2151-2156. 1995
1995 Effect of the arrangement of tandem repeating units of class A amphipathic α-helixes on lipid interactionJournal of Biological Chemistry.  270:1602-1611. 1995
1995 Effect of the cholesterol content of reconstituted LpA-I on lecithin:cholesterol acyltransferase activityJournal of Biological Chemistry.  270:5151-5157. 1995
1995 Efflux of Cellular Cholesterol and Phospholipid to Lipid-Free Apolipoproteins and Class A Amphipathic PeptidesBiochemistry.  34:7955-7965. 1995
1995 Identification and cholesterol quantification of low density lipoprotein subclasses in young adults by VAP-II methodologyJournal of Lipid Research.  36:2291-2302. 1995
1995 Lipolysis-induced partitioning of free fatty acids to lipoproteins: Effect on the biological properties of free fatty acidsJournal of Lipid Research.  36:1956-1970. 1995
1995 Mechanisms for the modulation of membrane bilayer properties by amphipathic helical peptidesBiopolymers.  37:319-338. 1995
1995 Microenvironments of Basic Amino Acids in Amphipathic a-Helices Bound to Phospholipid: 13C NMR Studies Using Selectively Labeled PeptidesBiochemistry.  34:9219-9226. 1995
1994 Binding of apolipoprotein A-I model peptides to lipid bilayers. Measurement of binding isotherms and peptide-lipid headgroup interactionsJournal of Biological Chemistry.  269:23904-23910. 1994
1994 The influence of apolipoprotein structure on the efflux of cellular free cholesterol to high density lipoproteinJournal of Biological Chemistry.  269:22975-22982. 1994
1994 ApoB-100 has a pentapartite structure composed of three amphipathic α-helical domains alternating with two amphipathic β-strand domains: Detection by the computer program LOCATEArteriosclerosis, Thrombosis and Vascular Biology.  14:1674-1685. 1994
1994 HDL and apolipoprotein A-I protect erythrocytes against the generation of procoagulant activityArteriosclerosis, Thrombosis and Vascular Biology.  14:1775-1783. 1994
1994 Interactions of synthetic peptide analogs of the class A amphipathic helix with lipids. Evidence for the snorkel hypothesisJournal of Biological Chemistry.  269:7185-7191. 1994
1994 Liposome-like particles isolated from human atherosclerotic plaques are structurally and compositionally similar to surface remnants of triglyceride- rich lipoproteinsArteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association.  14:622-635. 1994
1994 Mixing rates can markedly affect the kinetics of peptide-induced leakage from liposomesIUBMB Life.  33:1073-1079. 1994
1994 Pathogenesis of atherosclerosisCurrent Opinion in Cardiology.  9:404-410. 1994
1994 Quantification of cholesterol in all lipoprotein classes by the VAP-II methodJournal of Lipid Research.  35:159-168. 1994
1994 Synthetic amphipathic helical peptides that mimic apolipoprotein A-I in clearing cellular cholesterolJournal of Clinical Investigation.  94:1698-1705. 1994
1994 The amphipathic α helix: A multifunctional structural motif in plasma apolipoproteinsAdvances in Protein Chemistry.  45:303-369. 1994
1993 A mathematically defined motif for the radial distribution of charged residues on apolipoprotein amphipathic alpha helixesBiophysical Journal.  64:1827-1832. 1993
1993 Cytosolic domain of the human immunodeficiency virus envelope glycoproteins binds to calmodulin and inhibits calmodulin-regulated proteinsJournal of Biological Chemistry.  268:22895-22899. 1993
1993 Effect of end group blockage on the properties of a class A amphipathic helical peptideProteins: Structure, Function, and Bioinformatics.  15:349-359. 1993
1993 Reciprocal effects of apolipoprotein and lytic peptide analogs on membranes. Cross-sectional molecular shapes of amphipathic α helixes control membrane stabilityJournal of Biological Chemistry.  268:22112-22118. 1993
1993 Thyroid function and other clinical chemistry parameters in subjects eating iodine-enriched eggsFood and Chemical Toxicology.  31:247-251. 1993
1992 Are fusion peptides really "sided" insertional helices?Cell.  70:531-532. 1992
1992 Plasma lipoproteins in hyperlipidemic subjects eating iodine-enriched eggsJournal of the American College of Nutrition.  11:294-303. 1992
1992 Analysis for cholesterol in all lipoprotein classes by single vertical ultracentrifugation of fingerstick blood and controlled-dispersion flow analysisClinical Chemistry (Washington, DC): international journal of molecular diagnostics and laboratory medicine.  38:1898-1905. 1992
1992 Computer programs to identify and classify amphipathic α helical domainsJournal of Lipid Research.  33:287-296. 1992
1992 Membrane interactions of synthetic peptides corresponding to amphipathic helical segments of the human immunodeficiency virus type-1 envelope glycoproteinJournal of Biological Chemistry.  267:7121-7127. 1992
1992 Sexual differences in lipoprotein composition in a family with dyslipidemic hypertension with premature atheroschlerosis: Deficiency of high-density lipoprotein-L and high-density lipoprotein-M "apolipoprotein-I alone" particleTranslational Research: the journal of laboratory and clinical medicine.  119:57-68. 1992
1992 The amphipathic helix in the exchangeable apolipoproteins: A review of secondary structure and functionJournal of Lipid Research.  33:141-166. 1992
1992 Turnover of synthetic class A amphipathic peptide analogues of exchangeable apolipoproteins in rats: Correlation with physical propertiesArteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association.  12:886-894. 1992
1991 Apolipoprotein A-I decreases neutrophil degranulation and superoxide productionJournal of Lipid Research.  32:1911-1918. 1991
1991 Cytotoxicity of remnants of triglyceride-rich lipoproteins: An atherogenic insult?Advances in human genetics.  285:341-351. 1991
1991 Role of amphipathic helixes in HDL structure/functionAdvances in human genetics.  285:131-140. 1991
1991 Mean Field Stochastic Boundary Molecular Dynamics Simulation of a Phospholipid in a MembraneBiochemistry.  30:2099-2113. 1991
1991 Genetic and environmental contributions to cholesterol and its subfractions in 11-year-old twins: The medical college of virginia twin studyArteriosclerosis, Thrombosis and Vascular Biology.  11:844-850. 1991
1991 Inhibition of virus‐induced cell fusion by apolipoprotein A‐I and its amphipathic peptide analogsJournal of Cellular Biochemistry.  45:224-237. 1991
1991 Niacin revisited: Clinical observations on an important but underutilized drugAmerican Journal of Medicine.  91:239-246. 1991
1990 Nicotinic Acid in NIDDMJAMA: Journal of the American Medical Association.  264:2994-2995. 1990
1990 Thermodynamics of the binding of human apolipoprotein A-I to dimyristoylphosphatidylglycerolJournal of Biological Chemistry.  265:20829-20832. 1990
1990 Nuclear magnetic resonance investigation of the interaction with phospholipid of an amphipathic α-helix-forming peptide of the apolipoprotein classJournal of Biological Chemistry.  265:12217-12223. 1990
1990 Rechallenge With Crystalline Niacin After Drug-Induced Hepatitis From Sustained-Release NiacinJAMA: Journal of the American Medical Association.  264:241-243. 1990
1990 Interactions of Serum Proteins with Small Unilamellar Liposomes Composed of Dioleoylphosphatidylethanolamine and Oleic Acid: High-Density Lipoprotein, Apolipoprotein A1, and Amphipathic Peptides Stabilize LiposomesBiochemistry.  29:3637-3643. 1990
1990 Amphipathic helix motif: Classes and propertiesProteins: Structure, Function, and Bioinformatics.  8:103-117. 1990
1990 Antiviral effects of apolipoprotein A-I and its synthetic amphipathic peptide analogsVirology.  176:48-57. 1990
1990 Apolipoprotein A-I and its amphipathic helix peptide analogues inhibit human immunodeficiency virus-induced syncytium formationJournal of Clinical Investigation.  86:1142-1150. 1990
1990 Charge distributions and amphipathicity of receptor-binding alpha-helicesMolecular Immunology.  27:1009-1020. 1990
1990 Lipoprotein and oxygen transport alterations in passive smoking preadolescent children. The MCV Twin StudyCirculation.  81:586-592. 1990
1990 Use of synthetic peptide analogues to localize lecithin:cholesterol acyltransferase activating domain in apolipoprotein A-IArteriosclerosis (Dallas, Tex.).  10:95-105. 1990
1989 Identification of peptide hormones of the amphipathic helix class using the helical hydrophobic moment algorithmProteins: Structure, Function, and Bioinformatics.  6:61-69. 1989
1989 Lipolytic surface remnants of triglyceride-rich lipoproteins are cytotoxic to macrophages but not in the presence of high density lipoprotein. A possible mechanism of atherogenesis?Journal of Clinical Investigation.  83:1363-1374. 1989
1989 Properties of lipid complexes with amphipathic helix-forming peptides. Role of distribution of peptide chargesJournal of Biological Chemistry.  264:4628-4635. 1989
1989 Synthetic amphipathic peptides resembling apolipoproteins stimulate the release of human placental lactogenJournal of Biological Chemistry.  264:9215-9219. 1989
1988 Effect of oxidation on the properties of apolipoproteins A-1 and A-IIJournal of Lipid Research.  29:309-318. 1988
1987 Studies of synthetic peptide analogs of the amphipathic helix. Effect of charge distribution, hydrophobicity, and secondary structure on lipid association and lecithin:cholesterol acyltransferase activation.Journal of Biological Chemistry.  262:9389-9396. 1987
1987 The leader peptides from bacteriorhodopsin and halorhodopsin are potential membrane-spanning amphipathic helicesFEBS Letters.  213:238-240. 1987
1987 Characterization of high density lipoprotein subspecies: Structural studies by single vertical spin ultracentrifugation and immunoaffinity chromatographyJournal of Lipid Research.  28:913-929. 1987
1987 Effect of insulin therapy on lipoproteins in non-insulin dependent diabetes mellitus (NIDDM)Atherosclerosis.  67:105-114. 1987
1987 High-density lipoprotein-cholesterol subfractions in adolescent twinsPediatrics.  79:181-189. 1987
1986 Assays of the in Vitro Metabolism of Very-Low-Density Lipoproteins in Whole Plasma by Purified Lipoprotein LipaseMethods in Enzymology.  129:704-716. 1986
1986 [8] Single Vertical Spin Density Gradient UltracentrifugationMethods in Enzymology.  128:181-209. 1986
1985 Studies of synthetic peptide analogs of the amphiphatic helix. Correlation of structure with functionJournal of Biological Chemistry.  260:10256-10262. 1985
1985 Studies of synthetic peptide analogs of the amphiphatic helix. Structure of complexes with dimyristoyl phosphatidylcholineJournal of Biological Chemistry.  260:10248-10255. 1985
1985 Effects of glyburide therapy on lipoproteins in non-insulin-dependent diabetes mellitusAmerican Journal of Medicine.  79:86-91. 1985
1985 Influence of LCAT and core lipid transfer proteins (CLTP) reaction on the lipolytic conversion of VLDL into the LDL density fractionThe FASEB Journal.  44. 1985
1985 Microcomputer-based analysis of plasma lipoprotein subspeciesThe FASEB Journal.  44. 1985
1984 Structural Studies of Apolipoprotein A-I/Phosphatidylcholine Recombinants by High-Field Proton NMR, Nondenaturing Gradient Gel Electrophoresis, and Electron MicroscopyBiochemistry.  23:359-367. 1984
1983 Resistance of a very low density lipoprotein subpopulation from familial dysbetalipoproteinemia to in vitro lipolytic conversion to the low density lipoprotein density fractionJournal of Lipid Research.  24:1148-1159. 1983
1983 Plasma membrane-mediated leakage of liposomes induced by interaction with murine thymocytic leukemia cellsBBA: Biomembranes.  733:65-74. 1983
1983 Studies of synthetic peptide analogs of the amphipathic helix. Competitive displacement of exchangeable apolipoproteins from native lipoproteinsJournal of Biological Chemistry.  258:2290-2295. 1983
1983 Coronary heart disease risk. Assessment by plasma lipoprotein profiles.The Alabama journal of medical sciences.  20:76-83. 1983
1982 Computerized rapid high resolution quantitative analysis of plasma lipoproteins based upon single vertical spin centrifugationJournal of Lipid Research.  23:923-935. 1982
1982 Defective in vitro lipolysis of type IV hyperlipidemic human plasma by purified milk lipoprotein lipase. Studies by single vertical spin centrifugationJournal of Biological Chemistry.  257:7472-7480. 1982
1982 Structural domains of vesicular stomatitis virus. A study by differential scanning calorimetry, thermal gel analysis, and thermal electron microscopy.Journal of Biological Chemistry.  257:12-15. 1982
1982 Dynamics of Apolipoprotein-Phospholipid InteractionsBiophysical Journal.  37:172-173. 1982
1982 Effects of a high cholesterol meal on lipoprotein profiles analyzed by the vertical autoprofilerArteriosclerosis (Dallas, Tex.).  2. 1982
1982 Minimal Size Phosphatidylcholine Vesicles: Effects of Radius of Curvature on Head Group Packing and ConformationBiochemistry.  21:4569-4575. 1982
1982 Structural Domains in Vesicular Stomatitis Virus Membrane as Studied by Differential Scanning CalorimetryBiophysical Journal.  37:25-26. 1982
1982 Urinary Metabolites of CollagenMethods in Enzymology.  82:398-410. 1982
1981 High resolution plasma lipoprotein cholesterol profiles by a rapid, high volume semi-automated methodJournal of Lipid Research.  22:1003-1014. 1981
1981 Incorporation of the transmembrane hydrophobic domain of glycophorin into small unilamellar phospholipid vesicles Ion Flux studiesBBA: Biomembranes.  642:135-148. 1981
1980 Studies of synthetic peptide analogs of the amphipathic helix. Effect of charged amino acid residue topography on lipid affinity.Journal of Biological Chemistry.  255:11464-11472. 1980
1980 Preparative and quantitative isolation of plasma lipoproteins: rapid, single discontinuous density gradient ultracentrifugation in a vertical rotorJournal of Lipid Research.  21:284-291. 1980
1980 Liposome-cell interactions. A rapid assay for cells in suspension cultureBBA: Biomembranes.  596:420-425. 1980
1980 Detergent removal during membrane reconstitutionBBA: Biomembranes.  601:328-342. 1980
1979 Why high density lipoprotein: phospholipid recombinants cannot be spherical micellesFEBS Letters.  106:169-170. 1979
1979 High-density lipoprotein recombinants: evidence for a bicycle tire micelle structure obtained by neutron scattering and electron microscopyFEBS Letters.  104:231-235. 1979
1979 Isolation of glycophorin with deoxycholateBBA: Biomembranes.  554:533-537. 1979
1978 Binding of lithium diiodosalicylate to glycophorinBBA: Biomembranes.  511:297-301. 1978
1977 Interaction of the lipid-associating domain of glycophorin with phospholipid bilayers.Progress in clinical and biological research.  15:191-197. 1977
1977 Amphipathic helixes and plasma lipoproteins: A computer studyBiopolymers.  16:2053-2065. 1977
1977 Amphipathic helixes and plasma lipoproteins: Thermodynamic and geometric considerationsChemistry and Physics of Lipids.  18:7-22. 1977
1976 Molecular packing of high density lipoproteins: A postulated functional roleFEBS Letters.  69:111-115. 1976
1976 Amyloid A: Amphipathic Helixes and Lipid BindingBiochemistry.  15:3187-3191. 1976
1975 Proceedings: Lipid-protein interactions in biological membranes.Zeitschrift fur klinische Chemie und klinische Biochemie.  13:369. 1975
1975 The effects of the membrane-penetrating polypeptide segment of the human erythrocyte MN-glycoprotein on the permeability of model lipid membranesBBA: Biomembranes.  382:41-50. 1975
1975 The mechanism of lipid-binding by plasma lipoproteinsMolecular and Cellular Biochemistry: an international journal for chemical biology in health and disease.  6:43-50. 1975
1974 The interaction of apolipoprotein serine with phosphatidylcholineJournal of Biological Chemistry.  249:5314-5320. 1974
1974 Membrane proteins: Amino acid sequence and membrane penetrationJournal of Molecular Biology.  87:853-858. 1974
1974 A molecular theory of lipid-protein interactions in the plasma lipoproteinsFEBS Letters.  38:247-253. 1974
1974 Association of the membrane penetrating polypeptide segment of the human erythrocyte MN glycoprotein with phospholipid bilayers. I. Formation of freeze etch intramembranous particlesProceedings of the National Academy of Sciences of USA.  71:3294-3298. 1974
1973 Molecular features of the major glycoprotein of the human erythrocyte membraneThe FASEB Journal.  32:1833-1837. 1973
1973 Studies on the Major Sialoglycoprotein of the Human Red Cell Membrane. Isolation and Characterization of Tryptic GlycopeptidesBiochemistry.  12:3131-3138. 1973
1973 Major glycoprotein of the human erythrocyte membrane: Evidence for an amphipathic molecular structureArchives of Biochemistry and Biophysics.  155:167-183. 1973
1973 Science and societyScience.  182:336. 1973
1973 Unit fibril models derived from the molecular topography of collagenBiopolymers.  12:825-834. 1973
1972 Red cell membrane glycoprotein: Amino acid sequence of an intramembranous regionBiochemical and Biophysical Research Communications.  49:964-969. 1972
1972 Chemical characterization and surface orientation of the major glycoprotein of the human erythrocyte membrane.Proceedings of the National Academy of Sciences of USA.  69:1445-1449. 1972
1972 Molecular Weight Determination of Glycoproteins by Polyacrylamide Gel Electrophoresis in Sodium Dodecyl SulfateMethods in Enzymology.  28:54-63. 1972
1971 Molecular basis for fibrillar aggregation of tropocollagenNature.  234:26-28. 1971
1971 Human erythrocyte membrane glycoprotein: A re-evaluation of the molecular weight as determined by SDS polyacrylamide gel electrophoresisBiochemical and Biophysical Research Communications.  44:390-395. 1971
1970 A comparative study of glycopeptides derived from selected vertebrate collagens. A possible role of the carbohydrate in fibril formation.Journal of Biological Chemistry.  245:5042-5048. 1970
1970 Variations in human urinary O-hydroxylysyl glycoside levels and their relationship to collagen metabolism.Journal of Clinical Investigation.  49:1497-1509. 1970
1967 The isolation of identical hydroxylysyl glycosides from hydrolysates of soluble collagen and from human urine.Journal of Biological Chemistry.  242:2570-2571. 1967

Book

Year Title Altmetric
2002 Experimental and computational studies of the interactions of amphipathic peptides with lipid surfaces.  Ed. 52.  2002
1986 Preface.  Ed. 128.  1986

Education And Training

  • Doctorate in Biochemistry, Vanderbilt University 1969
  • Doctor of Medicine, Vanderbilt University 1967
  • Full Name

  • Jere Segrest