Positions

Overview

  • Dr. Bodduluri received his MS and PhD in Biomedical Engineering from the University of Iowa in 2016. He joined the pulmonary division as a research associate in 2016 under the mentorship of Dr. Surya Bhatt at the UAB Lung Imaging Core. Dr. Bodduluri’s research interest is to develop imaging solutions towards understanding the pathophysiology of pulmonary diseases using computer vision and machine learning approaches.

    • Selected Publications

    Academic Article

    Year Title Altmetric
    2023 Predicting severe chronic obstructive pulmonary disease exacerbations using quantitative CT: a retrospective model development and external validation study 2023
    2022 Acute Exacerbations Are Associated with Progression of Emphysema.  Annals of the American Thoracic Society.  19:2108-2111. 2022
    2022 Sex Differences in Airways at Chest CT: Results from the COPDGene Cohort.  Radiology.  305:699-708. 2022
    2022 New Guidelines for Bronchodilator Responsiveness in COPD: A Test in Search of a Use.  American Journal of Respiratory and Critical Care Medicine.  206:1042-1044. 2022
    2021 Extracellular Vesicle Mediated Tumor-Stromal Crosstalk Within an Engineered Lung Cancer Model.  Frontiers in Oncology.  11. 2021
    2021 Structural airway imaging metrics are differentially associated with persistent chronic bronchitis.  Thorax.  76:343-349. 2021
    2021 Association between inhaled corticosteroids and expiratory central airway collapse in smokers.  American Journal of Respiratory and Critical Care Medicine.  203:518-521. 2021
    2021 Computed tomography–based airway surface area–to-volume ratio for phenotyping airway remodeling in chronic obstructive pulmonary disease.  American Journal of Respiratory and Critical Care Medicine.  203:185-191. 2021
    2020 Deep neural network analyses of spirometry for structural phenotyping of chronic obstructive pulmonary disease.  JCI Insight.  5. 2020
    2020 Airway remodeling in ferrets with cigarette smoke-induced COPD using μCT imaging 2020
    2020 Brd4-p300 inhibition downregulates Nox4 and accelerates lung fibrosis resolution in aged mice.  JCI Insight.  5. 2020
    2019 The peak index: Spirometry metric for airflow obstruction severity and heterogeneity.  Annals of the American Thoracic Society.  16:982-989. 2019
    2019 Imaging advances in chronic obstructive pulmonary disease insights from the genetic epidemiology of chronic obstructive pulmonary disease (COPDGene) study.  American Journal of Respiratory and Critical Care Medicine.  199:286-301. 2019
    2019 COPDGene® 2019: Redefining the diagnosis of chronic obstructive pulmonary disease.  Chronic obstructive pulmonary diseases (Miami, Fla.).  6:384-399. 2019
    2019 Combined forced expiratory volume in 1 second and forced vital capacity bronchodilator response, exacerbations, and mortality in chronic obstructive pulmonary disease.  Annals of the American Thoracic Society.  16:826-835. 2019
    2018 Centrilobular emphysema and coronary artery calcification: Mediation analysis in the SPIROMICS cohort.  Respiratory Research.  19. 2018
    2018 Airway fractal dimension predicts respiratory morbidity and mortality in COPD.  Journal of Clinical Investigation.  128:5374-5382. 2018
    2018 Erratum: Airway fractal dimension predicts respiratory morbidity and mortality in COPD (Journal of Clinical Investigation (2018) 128:12 (5374–5382) DOI: 10.1172/JCI120693).  Journal of Clinical Investigation.  128:5676. 2018
    2018 New Spirometry Indices for Detecting Mild Airflow Obstruction.  Scientific Reports.  8. 2018
    2018 Visual Estimate of Coronary Artery Calcium Predicts Cardiovascular Disease in COPD.  Chest.  154:579-587. 2018
    2018 Paratracheal paraseptal emphysema and expiratory central airway collapse in smokers.  Annals of the American Thoracic Society.  15:479-484. 2018
    2018 Recent advances in computed tomography imaging in chronic obstructive pulmonary disease.  Annals of the American Thoracic Society.  15:281-289. 2018
    2017 Signs of gas trapping in normal lung density regions in smokers.  American Journal of Respiratory and Critical Care Medicine.  196:1404-1410. 2017
    2017 Computed tomography measure of lung at risk and lung function decline in chronic obstructive pulmonary disease.  American Journal of Respiratory and Critical Care Medicine.  196:569-576. 2017
    2017 Biomechanical CT metrics are associated with patient outcomes in COPD.  Thorax.  72:409-414. 2017
    2016 CT-derived Biomechanical Metrics Improve Agreement Between Spirometry and Emphysema.  Academic Radiology.  23:1255-1263. 2016
    2016 Computed tomography image matching in chronic obstructive pulmonary disease.  Critical Reviews in Biomedical Engineering.  44:411-425. 2016
    2015 Substrate Stiffness Affects Human Keratinocyte Colony Formation.  Cellular and Molecular Bioengineering.  8:32-50. 2015
    2013 Registration-based lung mechanical analysis of chronic obstructive pulmonary disease (COPD) using a supervised machine learning framework.  Academic Radiology.  20:527-536. 2013

    Research Overview

  • His research currently focuses on developing novel CT image-based metrics to phenotype COPD. Dr. Bodduluri is an active member of American Thoracic Society (ATS), European Respiratory Society (ERS), Society of Photographic Instrumentation Engineers (SPIE) and Biomedical Engineering Society (BMES).

    • Principal Investigator On

    Investigator On

    Education And Training

  • University of Iowa Department of Biomedical Engineering, Other
  • Doctor of Philosophy in Biomedical / Medical Engineering, University of Iowa 2016
  • Master of Sciences or Mathematics in Biomedical / Medical Engineering, University of Iowa 2012

    • Full Name

  • Sandeep Bodduluri