• Dr. Surolia received her PhD in Biochemistry from the University of Delhi South Campus in 2011. In 2011, she joined UAB’s Division of Pulmonary, Allergy, and Critical Care Medicine as postdoctoral fellow and subsequently assistant professor. Dr. Surolia is interested in understanding the molecular pathology of lung injury and repair related to environmental exposures and agents.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2023 Cutaneous Exposure to Arsenicals is Associated with Development of Constrictive Bronchiolitis in Mice.American Journal of Respiratory Cell and Molecular Biology2023
    2022 Pathophysiological Role of Vimentin Intermediate Filaments in Lung DiseasesFrontiers in Cell and Developmental Biology.  10. 2022
    2022 Fibrinogen mediates cadmium-induced macrophage activation and serves as a predictor of cadmium exposure in chronic obstructive pulmonary disease 2022
    2022 Targeting Cpt1a-Bcl-2 interaction modulates apoptosis resistance and fibrotic remodelingCell Death and Differentiation.  29:118-132. 2022
    2021 NETosis in the pathogenesis of acute lung injury following cutaneous chemical burnsJCI Insight.  6. 2021
    2021 Citrullinated vimentin mediates development and progression of lung fibrosisScience Translational Medicine.  13. 2021
    2020 Cutaneous lewisite exposure causes acute lung injuryAnnals of the New York Academy of Sciences.  1479:210-222. 2020
    2019 Increased flux through the mevalonate pathway mediates fibrotic repair without injuryJournal of Clinical Investigation.  129:4962-4978. 2019
    2019 Vimentin intermediate filament assembly regulates fibroblast invasion in fibrogenic lung injuryJCI Insight.  4. 2019
    2017 Autoimmunity to vimentin is associated with outcomes of patients with idiopathic pulmonary fibrosisJournal of Immunology.  199:1596-1605. 2017
    2017 Erratum: 3D pulmospheres serve as a personalized and predictive multicellular model for assessment of antifibrotic drugs (JCI Insight. (2017) 2:2 (e91377) DOI: 10.1172/jci.insight.91377)JCI Insight.  2. 2017
    2017 3D pulmospheres serve as a personalized and predictive multicellular model for assessment of antifibrotic drugs.JCI Insight.  2:e91377. 2017
    2017 Low-dose cadmium exposure induces peribronchiolar fibrosis through site-specific phosphorylation of vimentin 2017
    2016 Attenuated heme oxygenase-1 responses predispose the elderly to pulmonary nontuberculous mycobacterial infections 2016
    2015 Heme oxygenase-1-mediated autophagy protects against pulmonary endothelial cell death and development of emphysema in cadmium-treated mice 2015
    2015 Heme oxygenase-1 protects Corexit 9500ainduced respiratory epithelial injury across speciesPLoS One.  10. 2015
    2014 Wilms' tumor 1 (Wt1) regulates pleural mesothelial cell plasticity and transition into myofibroblasts in idiopathic pulmonary fibrosis 2014
    2013 Pleural mesothelial cell differentiation and invasion in fibrogenic lung injuryAmerican Journal of Pathology.  182:1239-1247. 2013
    2012 Heme oxygenase-1 promotes granuloma development and protects against dissemination of mycobacteriaLaboratory Investigation.  92:1541-1552. 2012
    2012 Preparation and characterization of monensin loaded PLGA nanoparticles: In vitro anti-malarial activity against Plasmodium falciparumJournal of Biomedical Nanotechnology.  8:172-181. 2012
    2011 Inhibition of the growth of plasmodium falciparum in culture by stearylamine-phosphatidylcholine liposomesJournal of Parasitology Research.  2011. 2011


    Year Title Altmetric
    2022 3D modeling of the lung in health and disease.  627-646. 2022

    Research Overview

  • Dr. Surolia's ongoing research projects involve toxic environmental exposure leading to COPD and pulmonary fibrosis. Currently, she has also successfully developed and characterized ex-vivo 3D model of lung tissue from patients with IPF. These ex-vivo 3D models are very important in basic research and translational medicine studies such as understanding various biological phenomenon of disease and repair mechanisms. They are an important tool to develop personalized therapies and to develop new drug targets.
  • Education And Training

  • Doctor of Philosophy in Biochemistry, University of Delhi 2011
  • Master of Sciences or Mathematics in Microbiology, University of Rajasthan 2006
  • Full Name

  • Ranu Surolia