Positions

Overview

  • Dr. Rui-Ming Liu received her M.D. and PhD (in Toxicology) degrees from Tongji Medical University, Wuhan, China. She is an American Board of Toxicology certified Toxicologist. Dr. Liu joined the UAB School of Public Health in 1999 as an Assistant Professor and was promoted to Associate Professor in 2005. In 2014, Dr. Liu was promoted to Professor with tenure and moved from School of Public Health to School of Medicine, Pulmonary, Allergy, and Critical Care Division.
  • Research Overview

  • Dr. Liu’s laboratory research focuses on oxidative stress, aging, and aging-related diseases, mainly Idiopathic Pulmonary Fibrosis (IPF). Her lab is interested in the etiologies and pathogeneses as well as the development of therapeutics for the treatment of these diseases. Specifically, the lab is interested in the mechanism and biological significance of depletion of glutathione (GSH), the most abundant intracellular free thiol and an important antioxidant, during aging and in IPF; the mechanisms whereby plasminogen activator inhibitor 1 (PAI-1), a physiological inhibitor of urokinase type and tissue type plasminogen activators, promotes cell senescence, aging, and fibrosis as well as the therapeutic potential of small molecule of PAI-1 inhibitors for the treatment of lung fibrotic diseases; and Interaction between genetic and environmental factors as well as aging in the onset of Alzheimer’s disease.
  • Education And Training

  • Doctor of Philosophy in Environmental Toxicology, Tongji University 1988
  • Master of Science in Environmental Toxicology, Tongji University 1985
  • Doctor of Medicine, Tongji University 1982
  • Full Name

  • Rui-Ming Liu