Selected Publications

Academic Article

Year Title Altmetric
2023 Post-randomization Differences in Condomless Vaginal Sex Among Women Randomized to Intramuscular Depot Medroxyprogesterone Acetate Injections, a Copper Intrauterine Device or a Levonorgestrel Implant in the ECHO TrialAIDS and Behavior.  27:978-983. 2023
2023 Non-barrier contraceptive use patterns among Latina adolescents attending California reproductive health centers: A longitudinal studyContraception.  118. 2023
2023 A novel “HIV salience and Perception” scale is associated with PrEP dispensing and adherence among adolescent girls and young women in Kampala, UgandaAIDS and Behavior.  27:279-289. 2023
2022 Genital microbiota of women using a 90 day tenofovir or tenofovir and levonorgestrel intravaginal ring in a placebo controlled randomized safety trial in KenyaScientific Reports.  12. 2022
2022 Using routine programmatic data to measure HIV incidence among pregnant women in BotswanaPopulation Health Metrics.  20. 2022
2022 Acceptability of an intravaginal ring for simultaneously preventing HIV infection and pregnancy: Qualitative findings of the Kisumu combined ring study, 2019Contemporary Clinical Trials.  122. 2022
2022 Bone mineral density, nutrient intake, and physical activity among young women from UgandaArchives of Osteoporosis.  17:134. 2022
2022 HIV Prevention Tools Across the Pregnancy Continuum: What Works, What Does Not, and What Can We Do Differently?Current HIV/AIDS Reports.  19:293-300. 2022
2022 High Levels of Pretreatment HIV-1 Drug Resistance Mutations Among South African Women Who Acquired HIV During a Prospective Study 2022
2022 PrEP uptake and HIV viral suppression when PrEP is integrated into Ugandan ART clinics for HIV-negative members of HIV-serodifferent couples: A stepped wedge cluster randomized trialEClinicalMedicine.  52. 2022
2022 The Effect of Contraception on Genital Cytokines in Women Randomized to Copper Intrauterine Device, Depot Medroxyprogesterone Acetate, or Levonorgestrel ImplantJournal of Infectious Diseases.  226:907-919. 2022
2022 Quantifiable Plasma Tenofovir Among South African Women Using Daily Oral Pre-exposure Prophylaxis During the ECHO Trial 2022
2022 HIV prevention metrics: lessons to be learned from contraceptionJournal of the International AIDS Society.  25. 2022
2022 An empiric tool to identify Kenyans living with HIV who will have unsuppressed viremia 18 months following treatment initiation to guide differentiated care modelsPLoS One.  17. 2022
2022 PrEP use and HIV seroconversion rates in adolescent girls and young women from Kenya and South Africa: the POWER demonstration projectJournal of the International AIDS Society.  25. 2022
2022 High HIV incidence among young women in South Africa: Data from a large prospective studyPLoS One.  17. 2022
2022 Health Care Worker Perspectives of HIV Pre-exposure Prophylaxis Service Delivery in Central UgandaFrontiers in Public Health.  10. 2022
2022 A pragmatic approach to identifying implementation barriers and facilitators for a novel pre-exposure prophylaxis (PrEP) delivery model at public facilities in urban Uganda.Implementation Science Communications.  3:7. 2022
2022 ART initiation among women newly diagnosed with HIV in a contraceptive trial in sub-Saharan Africa 2022
2022 “PrEP Gives the Woman the Control”: Healthcare Worker Perspectives on Using pre-Exposure Prophylaxis (PrEP) During Pregnancy and Postpartum in KenyaJournal of the International Association of Providers of AIDS Care.  21. 2022
2021 Comparison of Female Genital Tract Cytokine and Microbiota Signatures Induced by Initiation of Intramuscular DMPA and NET-EN Hormonal Contraceptives - a Prospective Cohort AnalysisFrontiers in Immunology.  12. 2021
2021 Use of fertility awareness methods as a component of safer conception for women in HIV-serodifferent relationships in KenyaReproductive Health.  18. 2021
2021 Adolescent girls and young women's PrEP-user journey during an implementation science study in South Africa and KenyaPLoS One.  16. 2021
2021 Recent Advances and New Challenges in Cisgender Women's Gynecologic and Obstetric Health in the Context of HIVClinical Obstetrics and Gynecology.  64:475-490. 2021
2021 Incorporating oral PrEP into standard prevention services for South African women: a nested interrupted time-series studyLancet HIV.  8:e495-e501. 2021
2021 Perceived Social Influences on Women's Decisions to use Medications not Studied in Pregnancy. A Qualitative Ethical Analysis of Preexposure Prophylaxis Implementation Research in KenyaJournal of Empirical Research on Human Research Ethics.  16:225-237. 2021
2021 Kidney injury biomarkers during exposure to tenofovir-based preexposure prophylaxisAIDS.  35:1147-1149. 2021
2021 HIV risk and pre-exposure prophylaxis interest among women seeking post-abortion care in Kenya: a cross-sectional studyJournal of the International AIDS Society.  24. 2021
2021 The Complex Link between the Female Genital Microbiota, Genital Infections, and InflammationInfection and Immunity.  89. 2021
2021 “Being a Person of Color in This Institution Is Exhausting”: Defining and Optimizing the Learning Climate to Support Diversity, Equity, and Inclusion at the University of Washington School of Public HealthFrontiers in Public Health.  9. 2021
2021 Correlates of HIV Status Nondisclosure by Pregnant Women Living With HIV to Their Male Partners in Uganda: A Cross-Sectional Study 2021
2021 Exploring the Use of Oral Pre-exposure Prophylaxis (PrEP) Among Women from Durban, South Africa as Part of the HIV Prevention Package in a Clinical TrialAIDS and Behavior.  25:1112-1119. 2021
2020 Vaginal microbiome-hormonal contraceptive interactions associate with the mucosal proteome and HIV acquisitionPLoS Pathogens.  16. 2020
2020 Adherence to recommendations for ART and targeted PrEP use among HIV serodiscordant couples in East Africa: the “PrEP as a bridge to ART” strategyBMC Public Health.  20. 2020
2020 Design of a care pathway for pharmacy-based PrEP delivery in Kenya: results from a collaborative stakeholder consultationBMC Health Services Research.  20. 2020
2020 Alignment of PrEP use and effective contraceptive use among East African women in HIV serodiscordant partnershipsInternational Journal of STD and AIDS.  31:1263-1271. 2020
2020 Depot medroxyprogesterone acetate use and blood lead levels in a cohort of young womenEnvironmental Health Perspectives.  128:117004-1-117004-7. 2020
2020 Age-Specific Risk Scores Do Not Improve HIV-1 Prediction Among Women in South Africa 2020
2020 Knowledge and barriers of PrEP delivery among diverse groups of potential PrEP users in Central UgandaPLoS One.  15. 2020
2020 Sexual behaviors after prep discontinuation among HIV serodiscordant couples in kenya and uganda 2020
2020 Defining gaps in pre-exposure prophylaxis delivery for pregnant and post-partum women in high-burden settings using an implementation science frameworkLancet HIV.  7:e582-e592. 2020
2020 Effects of Depot Medroxyprogesterone Acetate, Copper Intrauterine Devices, and Levonorgestrel Implants on Early HIV Disease ProgressionAIDS Research and Human Retroviruses.  36:632-640. 2020
2020 Sexual Behavior and Perceived HIV Risk Among HIV-Negative Members of Serodiscordant Couples in East AfricaAIDS and Behavior.  24:2082-2090. 2020
2020 The Effect of Depression on Adherence to HIV Pre-exposure Prophylaxis Among High-Risk South African Women in HPTN 067/ADAPTAIDS and Behavior.  24:2178-2187. 2020
2020 Integrating oral PrEP delivery among African women in a large HIV endpoint-driven clinical trialJournal of the International AIDS Society.  23. 2020
2020 No Evidence of Sexual Risk Compensation Following PrEP Initiation Among Heterosexual HIV Serodiscordant Couples in Kenya and UgandaAIDS and Behavior.  24:1365-1375. 2020
2020 The influence of HIV-related stigma on PrEP disclosure and adherence among adolescent girls and young women in HPTN 082: a qualitative studyJournal of the International AIDS Society.  23. 2020
2020 Cognitive testing of the PHQ-9 for depression screening among pregnant and postpartum women in KenyaBMC Psychiatry.  20. 2020
2020 Comparison of pregnancy incidence among African women in a randomized trial of intramuscular depot medroxyprogesterone acetate (DMPA-IM), a copper intrauterine device (IUDs) or a levonorgestrel (LNG) implant for contraceptionContraception: X.  2. 2020
2020 Emerging evidence from a systematic review of safety of pre-exposure prophylaxis for pregnant and postpartum women: where are we now and where are we heading?Journal of the International AIDS Society.  23. 2020
2019 PrEP Discontinuation and Prevention-Effective Adherence: Experiences of PrEP Users in Ugandan HIV Serodiscordant Couples 2019
2019 Impact of Tenofovir-Based Pre-exposure Prophylaxis on Biomarkers of Bone Formation, Bone Resorption, and Bone Mineral Metabolism in HIV-Negative AdultsOpen Forum Infectious Diseases.  6. 2019
2019 Lessons from PrEP: A Qualitative Study Investigating How Clinical and Policy Experts Weigh Ethics and Evidence When Evaluating Preventive Medications for Use in Pregnant and Breastfeeding WomenAIDS and Behavior.  23:1858-1870. 2019
2019 Corrigendum to “Pharmacokinetic, biologic and epidemiologic differences in MPA- and NET-based progestin-only injectable contraceptives relative to the potential impact on HIV acquisition in women” (Contraception (2019) 99(4) (199–204), (S0010782418305249), (10.1016/j.contraception.2018.12.001))Contraception.  100:88. 2019
2019 Perceptions of pregnancy occurring among HIV-serodiscordant couples in KenyaReproductive Health.  16. 2019
2019 Short Message Service (SMS) Surveys Assessing Pre-exposure Prophylaxis (PrEP) Adherence and Sexual Behavior are Highly Acceptable Among HIV-Uninfected Members of Serodiscordant Couples in East Africa: A Mixed Methods StudyAIDS and Behavior.  23:1267-1276. 2019
2019 Implementation of a comprehensive safer conception intervention for HIV-serodiscordant couples in Kenya: uptake, use and effectivenessJournal of the International AIDS Society.  22. 2019
2019 Pharmacokinetic, biologic and epidemiologic differences in MPA- and NET-based progestin-only injectable contraceptives relative to the potential impact on HIV acquisition in womenContraception.  99:199-204. 2019
2019 HIV risk associated with serum medroxyprogesterone acetate levels among women in East and southern AfricaAIDS.  33:735-744. 2019
2019 Tenofovir-diphosphate as a marker of HIV pre-exposure prophylaxis use among east african men and womenFrontiers in Pharmacology.  10. 2019
2019 The Incremental Cost of Delivering PrEP as a Bridge to ART for HIV Serodiscordant Couples in Public HIV Care Clinics in KenyaAIDS Research and Treatment.  2019. 2019
2018 HIV-Uninfected Kenyan Adolescent and Young Women Share Perspectives on Using Pre-Exposure Prophylaxis during Pregnancy 2018
2018 Patterns of Oral PrEP Adherence and HIV Risk Among Eastern African Women in HIV Serodiscordant PartnershipsAIDS and Behavior.  22:3718-3725. 2018
2018 Safer conception among HIV-1 serodiscordant couples in East Africa: understanding knowledge, attitudes, and experiences 2018
2018 Increased Risk of HIV Acquisition among Women Throughout Pregnancy and during the Postpartum Period: A Prospective Per-Coital-Act Analysis among Women with HIV-Infected PartnersJournal of Infectious Diseases.  218:16-25. 2018
2018 Consensus statement: Supporting Safer Conception and Pregnancy For Men And Women Living with and Affected by HIVAIDS and Behavior.  22:1713-1724. 2018
2018 Fertility Intentions, Pregnancy, and Use of PrEP and ART for Safer Conception Among East African HIV Serodiscordant CouplesAIDS and Behavior.  22:1758-1765. 2018
2018 Maternal hepatitis B infection and pregnancy outcomes in the United States: A population-based cohort studyOpen Forum Infectious Diseases.  5. 2018
2018 Integrated delivery of antiretroviral treatment and pre-exposure prophylaxis to HIV-1 serodiscordant couples in East Africa: a qualitative evaluation study in UgandaJournal of the International AIDS Society.  21. 2018
2018 Concordance of self-reported hormonal contraceptive use and presence of exogenous hormones in serum among African womenContraception.  97:357-362. 2018
2018 Simultaneous quantitation of multiple contraceptive hormones in human serum by LC–MS/MSContraception.  97:363-369. 2018
2018 High Levels of Viral Suppression among East African HIV-Infected Women and Men in Serodiscordant Partnerships Initiating Antiretroviral Therapy with High CD4 Counts and during PregnancyAIDS Research and Human Retroviruses.  34:140-147. 2018
2018 Intimate Partner Violence and Self-Reported Pre-exposure Prophylaxis Interruptions Among HIV-Negative Partners in HIV Serodiscordant Couples in Kenya and Uganda 2018
2018 Fertility desires and preferences for safer conception strategies among people receiving care for HIV at a publicly-funded clinic in Seattle, WA 2018
2018 Comparison of short messaging service self-reported adherence with other adherence measures in a demonstration project of HIV preexposure prophylaxis in Kenya and UgandaAIDS.  32:2237-2245. 2018
2018 Global and national guidance for the use of pre-exposure prophylaxis during peri-conception, pregnancy and breastfeedingSexual Health.  15:501-512. 2018
2018 PrEP Use During Periods of HIV Risk Among East African Women in Serodiscordant Relationships 2018
2018 Pregnancy outcomes and infant growth among babies with in-utero exposure to tenofovir-based preexposure prophylaxis for HIV preventionAIDS.  32:1707-1713. 2018
2018 Tenofovir and tenofovir-diphosphate concentrations during pregnancy among HIV-uninfected women using oral preexposure prophylaxisAIDS.  32:1891-1898. 2018
2017 Maternal Tenofovir Disoproxil Fumarate Use during Pregnancy Is Not Associated with Adverse Perinatal Outcomes among HIV-infected East African Women: A Prospective StudyJournal of Infectious Diseases.  216:1561-1568. 2017
2017 The role of male partners in women's participation in research during pregnancy: A case study from the partners demonstration projectReproductive Health.  14. 2017
2017 " i Did Not Want to Give Birth to a Child Who has HIV ": Experiences Using PrEP during Pregnancy among HIV-Uninfected Kenyan Women in HIV-Serodiscordant Couples 2017
2017 The Vaginal Microbiome and its Potential to Impact Efficacy of HIV Pre-exposure Prophylaxis for WomenCurrent HIV/AIDS Reports.  14:153-160. 2017
2017 Depression and ART Initiation Among HIV Serodiscordant Couples in Kenya and UgandaAIDS and Behavior.  21:2509-2518. 2017
2017 Objective Measurement of Inaccurate Condom Use Reporting Among Women Using Depot Medroxyprogesterone Acetate for ContraceptionAIDS and Behavior.  21:2173-2179. 2017
2017 Could misreporting of condom use explain the observed association between injectable hormonal contraceptives and HIV acquisition risk?Contraception.  95:424-430. 2017
2017 A Risk Assessment Tool for Identifying Pregnant and Postpartum Women Who May Benefit From Preexposure ProphylaxisClinical Infectious Diseases.  64:751-758. 2017
2017 Delivering safer conception services to HIV serodiscordant couples in Kenya: Perspectives from healthcare providers and HIV serodiscordant couplesJournal of the International AIDS Society.  20:52-58. 2017
2017 Feasibility and acceptability of HIV self-testing among pre-exposure prophylaxis users in KenyaJournal of the International AIDS Society.  20. 2017
2017 Adverse birth outcomes and maternal Neisseria gonorrhoeae infection: A population-based cohort study in Washington StateSexually Transmitted Diseases.  44:266-271. 2017
2017 Alignment of adherence and risk for HIV acquisition in a demonstration project of pre-exposure prophylaxis among HIV serodiscordant couples in Kenya and Uganda: A prospective analysis of prevention-effective adherence: AJournal of the International AIDS Society.  20. 2017
2017 Context matters: PrEP adherence is associated with sexual behavior among HIV serodiscordant couples in East Africa 2017
2017 Counseling framework for HIV-serodiscordant couples on the integrated use of antiretroviral therapy and pre-exposure prophylaxis for HIV prevention 2017
2017 Effect of Pregnancy on Response to Antiretroviral Therapy in HIV-Infected African Women 2017
2017 Efficacy of oral pre-exposure prophylaxis (PrEP) for HIV among women with abnormal vaginal microbiota: a post-hoc analysis of the randomised, placebo-controlled Partners PrEP StudyLancet HIV.  4:e449-e456. 2017
2017 Hormonal contraception is not associated with reduced art effectiveness among women initiating art: Evidence from longitudinal data 2017
2017 Pre-exposure prophylaxis for HIV-negative persons with partners living with HIV: Uptake, use, and effectiveness in an open-label demonstration project in East AfricaGates Open Research.  1. 2017
2017 Rationale and design of a multi-center, open-label, randomised clinical trial comparing HIV incidence and contraceptive benefits in women using three commonly-used contraceptive methods (The ECHO study)Gates Open Research.  1. 2017
2016 “I never thought that it would happen … ” Experiences of HIV seroconverters among HIV-discordant partnerships in a prospective HIV prevention study in Kenya 2016
2016 Use of a risk scoring tool to identify higher-risk HIV-1 serodiscordant couples for an antiretroviral-based HIV-1 prevention interventionBMC Infectious Diseases.  16. 2016
2016 Integrated Delivery of Antiretroviral Treatment and Pre-exposure Prophylaxis to HIV-1–Serodiscordant Couples: A Prospective Implementation Study in Kenya and UgandaPLoS Medicine.  13. 2016
2016 Perceived Risk among Human Immunodeficiency Virus Serodiscordant Couples in East Africa Taking Oral Pre-Exposure ProphylaxisSexually Transmitted Diseases.  43:471-475. 2016
2016 Seminal HIV-1 RNA Detection in Heterosexual African Men Initiating Antiretroviral TherapyJournal of Infectious Diseases.  214:212-215. 2016
2016 PrEP as Peri-conception HIV Prevention for Women and MenCurrent HIV/AIDS Reports.  13:131-139. 2016
2016 The Effect of Human Immunodeficiency Virus Prevention and Reproductive Health Text Messages on Human Immunodeficiency Virus Testing among Young Women in Rural Kenya: A Pilot StudySexually Transmitted Diseases.  43:353-359. 2016
2016 Gendered differences in the perceived risks and benefits of oral PrEP among HIV-serodiscordant couples in Kenya 2016
2016 I knew I would be safer. Experiences of Kenyan HIV serodiscordant couples soon after pre-exposure prophylaxis (PrEP) initiation 2016
2016 Tenofovir-based oral preexposure prophylaxis prevents HIV infection among womenCurrent Opinion in HIV and AIDS.  11:18-26. 2016
2015 A discussion of key values to inform the design and delivery of services for HIV-affected women and couples attempting pregnancy in resource-constrained settingsJournal of the International AIDS Society.  18. 2015
2015 A scoring tool to identify East African HIV-1 serodiscordant partnerships with a high likelihood of pregnancyPLoS One.  10. 2015
2015 Effectiveness of hormonal contraception in HIV-infected women using antiretroviral therapyAIDS.  29:2353-2359. 2015
2015 Fertility Decision-Making among Kenyan HIV-Serodiscordant Couples Who Recently Conceived: Implications for Safer Conception Planning 2015
2015 Cost-effectiveness of pre-exposure prophylaxis targeted to high-risk serodiscordant couples as a bridge to sustained ART use in Kampala, UgandaJournal of the International AIDS Society.  18. 2015
2015 Contraception and sexually transmitted infections: Risks and benefits, hypotheses and evidence 2015
2015 Hormonal Contraception and the Risk of HIV Acquisition: An Individual Participant Data Meta-analysisPLoS Medicine.  12:1-26. 2015
2014 My intention was a child but i was very afraid: Fertility intentions and HIV risk perceptions among HIV-serodiscordant couples experiencing pregnancy in Kenya 2014
2014 High medication adherence during periconception periods among HIV-1-uninfected women participating in a clinical trial of antiretroviral pre-exposure prophylaxis 2014
2014 Pre-exposure prophylaxis does not affect the fertility of HIV-1-uninfected menAIDS.  28:1977-1982. 2014
2014 Pre-exposure prophylaxis for HIV-1 prevention does not diminish the pregnancy prevention effectiveness of hormonal contraceptionAIDS.  28:1825-1830. 2014
2014 Pregnancy incidence and outcomes among women receiving preexposure prophylaxis for HIV prevention: A randomized clinical trialJournal of the American Medical Association.  312:362-371. 2014
2014 A prospective study of the effect of pregnancy on CD4 counts and plasma HIV-1 RNA concentrations of antiretroviral-naive HIV-1-infected women 2014
2014 If i am given antiretrovirals i will think i am nearing the grave': Kenyan HIV serodiscordant couples' attitudes regarding early initiation of antiretroviral therapyAIDS.  28:227-233. 2014
2014 Association between male circumcision and incidence of syphilis in men and women: A prospective study in HIV-1 serodiscordant heterosexual African couples 2014
2014 Pre-exposure prophylaxis to intensify the fight against HIVLancet Infectious Diseases.  14:443-445. 2014
2014 Preexposure prophylaxis is efficacious for HIV-1 prevention among women using depot medroxyprogesterone acetate for contraceptionAIDS.  28:2771-2776. 2014
2014 Preferences for daily or intermittent pre-exposure prophylaxis regimens and ability to anticipate sex among HIV uninfected members of Kenyan HIV serodiscordant couplesAIDS and Behavior.  18:1701-1711. 2014
2013 Daily short message service surveys to measure sexual behavior and pre-exposure prophylaxis use among kenyan men and womenAIDS and Behavior.  17:2977-2985. 2013
2013 Assessing the effect of hormonal contraception on HIV acquisition in observational data: challenges and recommended analytic approachesAIDS.  27. 2013
2013 Fertility intentions and interest in early antiretroviral therapy among east African HIV-1-infected individuals in serodiscordant partnerships 2013
2013 Hormonal contraceptive use and risk of HIV-1 disease progressionAIDS.  27:261-267. 2013
2012 Willingness of Kenyan HIV-1 serodiscordant couples to use antiretroviral-based HIV-1 prevention strategies 2012
2012 Use of hormonal contraceptives and risk of HIV-1 transmission - Authors' replyLancet Infectious Diseases.  12:510-511. 2012
2012 Correlates of contraceptive use among HIV discordant couples in Kenya 2012
2012 Contraceptive method and pregnancy incidence among women in HIV-1-serodiscordant partnershipsAIDS.  26:513-518. 2012
2012 Use of hormonal contraceptives and risk of HIV-1 transmission: A prospective cohort studyLancet Infectious Diseases.  12:19-26. 2012
2011 Optimal uses of antiretrovirals for prevention in HIV-1 serodiscordant heterosexual couples in South Africa: A modelling studyPLoS Medicine.  8. 2011
2011 Increased risk of HIV-1 transmission in pregnancy: A prospective study among African HIV-1-serodiscordant couplesAIDS.  25:1887-1895. 2011
2011 High prevalent and incident HIV-1 and herpes simplex virus 2 infection among male migrant and non-migrant sugar farm workers in ZambiaSexually Transmitted Infections.  87:283-288. 2011
2011 Performance of the Focus HerpeSelect-2 enzyme immunoassay for the detection of herpes simplex virus type 2 antibodies in seven African countriesSexually Transmitted Infections.  87:238-241. 2011
2010 A prospective study of contraceptive use among African women in HIV-1 serodiscordant partnershipsSexually Transmitted Diseases.  37:621-628. 2010
2009 Successful increase in contraceptive uptake among Kenyan HIV-1-serodiscordant couples enrolled in an HIV-1 prevention trialAIDS.  23. 2009

Education And Training

  • Doctor of Philosophy in Epidemiology, University of Washington 2012
  • Master of Public Health, Tulane University 2004
  • Full Name

  • Renee Heffron