The sponge Dendrilla membranosa, a conspicuous member of the Antarctic benthos that appears to be free of predation, produces several norditerpenes, including the previously unreported dendrillin [1], as well as amino acid and nucleotide derivatives. The norditerpenes, previously implicated as chemical defense agents, displayed no deterrent effect toward the chemosensory tube-feet of the major Antarctic sponge predator, the sea star Perknaster fuscus. © 1995, American Chemical Society. All rights reserved.
