Lymph Node Metastases do not Impact Survival in Follicular Variant Papillary Thyroid Cancer

Academic Article

Abstract

  • Results: Of the 20,357 cases of FVPTC with lymph node data available, 1,761 (8.7%) had LNM; 61.1% of these LNM were located in the central neck and 38.9% were in the lateral neck. Extrathyroidal extension (odds ratio [OR] 2.6, 95% confidence interval [CI] 2.2-3.0, p < 0.01) and multifocality (OR 3.0, 95% CI 2.5–3.6, p < 0.01) were the strongest predictors of LNM. Importantly, LNM did not independently predict DSM (p = 0.52). Tumor size >4 cm (hazards ratio [HR] 5.3, 95% CI 2.2–12.8, p < 0.01) and extrathyroidal extension (HR 8.2, 95% CI 3.0–22.0, p < 0.01) were the strongest predictors of DSM.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Schneider DF; Elfenbein D; Lloyd RV; Chen H; Sippel RS
  • Start Page

  • 158
  • End Page

  • 163
  • Volume

  • 22
  • Issue

  • 1