Conductance changes induced by DL-homocysteic acid and N-methyl-DL-aspartic acid in hippocampal neurons

Academic Article


  • Iontophoretic application of DL-homocysteic acid or N-methyl-DL-aspartic acid to the dendrites of hippocampal neurons maintained in vitro caused membrane depolarizations that were associated with increases as well as decreases in input resistance. Increases in resistance were most prominent when low doses of agonists were applied. Both types of conductance change persisted after bath application of tetrodotoxin and manganese. © 1982.
  • Authors

    Published In

  • Brain Research  Journal
  • Digital Object Identifier (doi)

    Pubmed Id

  • 11414034
  • Author List

  • Hablitz JJ
  • Start Page

  • 149
  • End Page

  • 153
  • Volume

  • 247
  • Issue

  • 1