Reconstructing the infected aortic root with antibiotic impregnated biological glue

Academic Article


  • Prosthetic valve dehiscence and persistent infection are two complications following reconstruction of the aortic root in destructive endocarditis. A technique is described involving the principles of aggressive debridement, closure of large abscess cavities with biological material incorporating a slurry of antibiotic-impregnated biological sealant, and replacement of the aortic valve with an aortic allograft valve. This strategy appears to have been successful in preventing persistent endocarditis and valve dehiscence in a limited number of patients. © 2013 Wiley Periodicals, Inc.
  • Authors

    Published In

    Digital Object Identifier (doi)

    Author List

  • McGiffin DC; Davies JE; Kirklin JK
  • Start Page

  • 340
  • End Page

  • 342
  • Volume

  • 29
  • Issue

  • 3