Bilayer lipid membranes (BLM): Study of antigen-antibody interactions

Academic Article


  • Previous work of del Castillo and co-workers has shown that bilayer lipid membranes (BLM) can be used as transducers for detection of antigen-antibody reactions. The present experiments extend the previous work by incorporating complement into the BLM system. The results indicate that the antigen-antibody complex or the complement has no ability to affect the BLM system separately, but when carefully combined they will destabilize the BLM even at a much reduced concentration. Further development using the BLM as a tool for investigating immunological reactions is suggested. © 1979 Plenum Publishing Corporation.
  • Digital Object Identifier (doi)

    Author List

  • Mountz JD; Ti Tien H
  • Start Page

  • 139
  • End Page

  • 151
  • Volume

  • 10
  • Issue

  • 5-6