Urethral cytokine and immune responses in Chlamydia trachomatis-infected males

Academic Article


  • Penile urethral swabs collected from PCR-confirmed Chlamydia trachomatis-infected, C. trachomatis-uninfected, and non-C. trachomatis-infected, nongonococcal urethritis-infected males were analyzed for cytokine, total immunoglobulin (Ig), and specific antibody levels by enzyme-linked immunosorbent assay. Differential cellular components of the swab transport medium were also enumerated for the same groups. Although low, the levels of C. trachomatis-specific IgA and IgG antibodies and interleukin 8 cytokine were significantly higher in C. trachomatis-infected individuals. There were no significant differences in the levels of seven additional cytokines evaluated.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Pate MS; Hedges SR; Sibley DA; Russell MW; Hook EW; Mestecky J
  • Start Page

  • 7178
  • End Page

  • 7181
  • Volume

  • 69
  • Issue

  • 11