Successful treatment of disseminated Fusarium infection after autologous bone marrow transplantation for acute myeloid leukemia

Academic Article

Abstract

  • Disseminated Fusarium is a rare but life-threatening infection of severely immunocompromised patients. A fatal outcome has been described in all reported cases of Fusarium infection occurring after bone marrow transplantation. We describe a patient who developed disseminated Fusarium infection with a secondary fungal endophthalmitis after an autologous bone marrow transplant for acute myeloid leukemia. This infection was successfully eradicated after neutrophil recovery by prolonged systemic administration of amphotericin B as well as aggressive local therapy including enucleation of the affected eye. The patient remains free of both leukaemia and fungal disease more than 4 years after transplant.
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    Author List

  • Robertson MJ; Socinski MA; Soiffer RJ; Finberg RW; Wilson C; Anderson KC; Bosserman L; Sang DN; Salkin IF; Ritz J
  • Start Page

  • 143
  • End Page

  • 145
  • Volume

  • 8
  • Issue

  • 2