The Role of PIM Kinases in Pediatric Solid Tumors

Academic Article

Abstract

  • PIM kinases have been identified as potential therapeutic targets in several malignancies. Here, we provide an in-depth review of PIM kinases, including their structure, expression, activity, regulation, and role in pediatric carcinogenesis. Also included is a brief summary of the currently available pharmaceutical agents targeting PIM kinases and existing clinical trials.
  • Published In

  • Cancers  Journal
  • Digital Object Identifier (doi)

    Author List

  • Julson JR; Marayati R; Beierle EA; Stafman LL
  • Volume

  • 14
  • Issue

  • 15