A TIReless battle: TIR domains in plant–pathogen interactions

Academic Article


  • Toll/interleukin-1 receptor (TIR) domain-containing proteins are conserved across kingdoms, and their mechanistic understanding holds promise for basic plant biology and agriculture. Here, we discuss the novel enzymatic TIR domain functions of nucleotide-binding leucine-rich repeat receptors (NLRs) in cell death, and posit how TIR domain-containing effectors mechanistically subvert host immune systems.
  • Published In

    Digital Object Identifier (doi)

    Pubmed Id

  • 28318501
  • Author List

  • Liu J; Fakhar AZ; Pajerowska-Mukhtar KM; Mukhtar MS
  • Start Page

  • 426
  • End Page

  • 429
  • Volume

  • 27
  • Issue

  • 5