Preparation and Characterization of Superoxide Dismutase Soluble in Organic Solvents.

Academic Article


  • A glycolipid (2C(12)GE) is synthesized with glutamate, dodecanol and gluconolactone and a glycolipid-coated superoxide dismutase (SOD) is prepared by mixing an aqueous solution of the enzyme with the synthetic 2C(12)GE. The glycolipid-enzyme complex (SOD-2C(12)GE) is insoluble in water but soluble in organic solvents such as ethanol, acetone, glycerin and dioxane. It exhibits a higher activity in some organic solvents such as ethanol than in water and there is an optimum concentration in organic solvent for the catalytic reaction. The SOD-2C(12)GE is more stable against changes in temperature, pH and hydrolysis by protease than the native SOD.
  • Authors

    Published In

    Author List

  • Zou G-L; Xia L; Li P
  • Start Page

  • 83
  • End Page

  • 88
  • Volume

  • 28
  • Issue

  • 1