Generation and Profiling of Tumor-Homing Induced Neural Stem Cells from the Skin of Cancer Patients

Academic Article

Abstract

  • The conversion of fibroblasts into tumor-homing-personalized induced neural stem cells (iNSCs) is a promising approach for treating various types of cancer. We combine functional, genomic, and in vivo assays to investigate the efficacy and tumor-homing capacity of the first iNSCs derived from brain cancer patients, marking an important step toward clinical application.
  • Authors

    Published In

  • Molecular Therapy  Journal
  • Digital Object Identifier (doi)

    Author List

  • Buckley A; Hagler SB; Lettry V; Bag√≥ JR; Maingi SM; Khagi S; Ewend MG; Miller CR; Hingtgen SD
  • Start Page

  • 1614
  • End Page

  • 1627
  • Volume

  • 28
  • Issue

  • 7