Prevalence of vitreomacular adhesion in patients without maculopathy older than 40 years

Academic Article

Abstract

  • Purpose: To determine the prevalence and factors influencing vitreomacular adhesion (VMA) or vitreomacular traction (VMT) in subjects without maculopathy older than age 40 years. Methods: In a prospective cross-sectional study, 1,950 eyes in 1,090 participants aged 40 to 89 years representing various ethnic groups from 14 centers in the United States underwent a comprehensive eye examination, including spectral domain optical coherence tomography. A team of independent, masked readers classified the presence or absence of VMA/VMT on spectral domain optical coherence tomography based on the International Vitreomacular Traction Study Group rubric. Results: Across all eyes, the prevalence of VMA or VMT was 39% or 1%, respectively. For every 1-year increase in age, there was a statistically significant 7% decreased odds of having VMA or VMT (95% confidence interval [CI]: 0.89-0.96; P, 0.001), whereas African Americans had 55% significantly reduced odds of having VMA or VMT when than whites (95% CI: 0.23-0.90; P = 0.025). Vitreomacular adhesion .1,500 mm was significantly more likely than VMA,1,500 mm in younger adults (95% CI: 0.70-0.86; P, 0.001), hyperopes versus emmetropes (95% CI: 1.49-35.9; P = 0.01), primary eye care versus tertiary practices (95% CI: 0.03-0.92; P = 0.04), and patients without hyperlipidemia (95% CI: 0.04-0.83; P = 0.03). Conclusion: Vitreomacular adhesion is highly prevalent among middle-aged adults. Diagnostic screening with spectral domain optical coherence tomography may help to accurately detect VMA or VMT, prompting routine monitoring and timely therapeutic intervention.
  • Authors

    Digital Object Identifier (doi)

    Author List

  • Rodman JA; Shechtman D; Sutton BM; Pizzimenti JJ; Bittner AK; Wals K; Tolentino M; Ficco C; Smik K; Perez M
  • Start Page

  • 2056
  • End Page

  • 2063
  • Volume

  • 38
  • Issue

  • 10