Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 2.2019

Academic Article


  • Chronic lymphocytic leukemia (CLL) is generally characterized by an indolent disease course. Histologic transformation (also known as Richter’s transformation) to more aggressive lymphomas, such as diffuse large B-cell lymphoma or Hodgkin lymphoma, occurs in approximately 2% to 10% of patients and is associated with a poor prognosis. These NCCN Guidelines Insights discuss the recommendations for the diagnosis and management of patients with histologic transformation.
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    Author List

  • Wierda WG; Byrd JC; Abramson JS; Bilgrami SF; Bociek G; Brander D; Brown J; Chanan-Khan AA; Chavez JC; Coutre SE
  • Start Page

  • 12
  • End Page

  • 20
  • Volume

  • 17
  • Issue

  • 1