Intramedullary nail fixation is an excellent option for open reduction and internal fixation of metatarsal neck and shaft fractures. In the authors' experience, the reduction of these fractures with Steinmann pin fixation provided excellent stability, required minimal soft-tissue dissection, and allowed for preservation of the periosteal tissue. Minimal disruption to the periosteum protects the osteoprogenitor cells located in the cambium layer. These cells stimulate osteoblastic activity, allowing for excellent secondary bone healing. Intramedullary nail fixation is the authors' chosen procedure for reduction of lesser metatarsal fractures.