OBJECTIVE Contagious infectious diseases add a new dimension to radiology and pose many unanswered questions. In particular, what is the safest way to image patients with contagious and potentially lethal infectious diseases? Here, we describe protocols used by Emory University to successfully acquire chest radiographs of patients with Ebola virus disease. CONCLUSION. Radiology departments need to develop new protocols for various modalities used in imaging patients with contagious and potentially lethal infectious diseases.