Möbius syndrome in infant exposed to cocaine in utero

Academic Article


  • The pathophysiology of Möbius syndrome has been debated for decades. A vascular etiology is currently favored because it explains the wide clinical spectrum of this syndrome. An infant is reported who was born with Möbius syndrome after a pregnancy complicated by heavy maternal use of cocaine and alcohol. We speculate that cocaine-induced vasoconstriction at a critical time of cerebrovascular development produced a vascular disruption sequence leading to the Möbius syndrome. © 1993.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Kankirawatana P; Tennison MB; D'Cruz O; Greenwood RS
  • Start Page

  • 71
  • End Page

  • 72
  • Volume

  • 9
  • Issue

  • 1