Validity and interexaminer reliability of a new method to quantify skin neurofibromas of neurofibromatosis 1 using paper frames

Academic Article


  • BACKGROUND: Skin neurofibromas represent one of the main clinical manifestations of neurofibromatosis 1, and their number varies greatly between individuals. Quantifying their number is an important step in the methodology of many clinical studies, but counting neurofibromas one by one in individuals with thousands of tumors is arduous, time-consuming, and subject to intra and interexaminer variability. We aimed to evaluate the efficacy of a new methodology for skin neurofibromas quantification using paper frames.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Cunha KSG; Rozza-de-Menezes RE; Andrade RM; Theos A; Luiz RR; Korf B; Geller M
  • Start Page

  • 202
  • Volume

  • 9