Hyperoxia causes MIR-34a-mediated injury via angiopoietin-1 in neonatal lungs

Academic Article


  • Hyperoxia contributes to lung injury in bronchopulmonary dysplasia. The authors show that hyperoxia increases miR-34a expression in human neonates and in mouse models, and that pathology is ameliorated by miR-34a inhibition or by administration of its target angiopoietin-1.
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    Digital Object Identifier (doi)

    Author List

  • Syed M; Das P; Pawar A; Aghai ZH; Kaskinen A; Zhuang ZW; Ambalavanan N; Pryhuber G; Andersson S; Bhandari V
  • Volume

  • 8
  • Issue

  • 1