Non-arteritic anterior ischaemic optic neuropathy and presumed sleep apnoea syndrome screened by the sleep apnea scale of the sleep disorders questionnaire (SA-SDQ)

Academic Article


  • Background: Two recent studies reported over 70% of the patients with non-arteritic anterior ischaemic optic neuropathy (NAION) had sleep apnoea syndrome (SAS) diagnosed by overnight polysomnography. The current study used the Sleep Apnea scale of the Sleep Disorders Questionnaire (SA-SDQ) to evaluate this association. Methods: A matched case-control study was conducted among 73 cases of NAION matched on age and gender to 73 controls without a history of NAION. Information regarding demographics, medical conditions, health behaviours and SAS was obtained via a telephone questionnaire that included the SA-SDQ. Conditional logistic regression was used to calculate odds ratios (OR) and the 95% confidence intervals (CI) for the association between NAION and the SA-SDQ. Results: Cases were significantly more likely to report symptoms and characteristics consistent with SAS than controls (OR 2.62; 95% CI 1.03 to 6.60) when adjusted for medical and health behaviour characteristics. Conclusions: The results of this study suggest that patients with SAS are at increased risk of NAION. Additional research in a larger population is needed to confirm the observed results and validate the use of the SA-SDQ in patients with NAION.
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    Digital Object Identifier (doi)

    Author List

  • Li J; McGwin G; Vaphiades MS; Owsley C
  • Start Page

  • 1524
  • End Page

  • 1527
  • Volume

  • 91
  • Issue

  • 11