DNA rearrangements and phenotypic switching in prokaryotes

Academic Article


  • Microorganisms have numerous strategies for coping with environmental changes. In many systems, a single cell has the capacity to generate a seemingly infinite array of phenotypic variants in just a few generations of growth. The resulting heterogeneous population is well equipped for sudden environmental change; even if only a few cells in the population possess a phenotype needed for survival, these cells have the capacity to regenerate a similarly diverse population. Phenotypic switching in these systems usually results from high‐frequency DNA rearrangements which are the subject of this review. Copyright © 1993, Wiley Blackwell. All rights reserved
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Dybvig K
  • Start Page

  • 465
  • End Page

  • 471
  • Volume

  • 10
  • Issue

  • 3