Technical note: Heterogeneity dose calculation accuracy in IMRT: Study of five commercial treatment planning systems using an anthropomorphic thorax phantom

Academic Article


  • The purpose of this study was to determine the accuracy of five commonly used intensity-modulated radiation therapy (IMRT) treatment planning systems (TPSs), 3 using convolution superposition algorithms or the analytical anisotropic algorithm (CSA/AAAs) and 2 using pencil beam algorithms (PBAs), in calculating the absorbed dose within a low-density, heterogeneous region when compared with measurements made in an anthropomorphic thorax phantom. The dose predicted in the target center met the test criteria (5% of the dose normalization point or 3 mm distance to agreement) for all TPSs tested; however, at the tumor-lung interface and at the peripheral lung in the vicinity of the tumor, the CSA/AAAs performed better than the PBAs (85% and 50%, respectively, of pixels meeting the 5%/3-mm test criteria), and thus should be used to determine dose in heterogeneous regions. © 2008 American Association of Physicists in Medicine.
  • Published In

  • Medical Physics  Journal
  • Medical Physics  Journal
  • Digital Object Identifier (doi)

    Author List

  • Davidson SE; Popple RA; Ibbott GS; Followill DS
  • Start Page

  • 5434
  • End Page

  • 5439
  • Volume

  • 35
  • Issue

  • 12