The preparation of 2-(1-phenyl-5-phenyl or 5-substituted phenyl-1H- pyrazol-3-yl)phenols from trilithiated 2'-hydroxyacetophenone phenylhydrazone and aromatic esters

Academic Article


  • 2'-Hydroxyacetophenone phenylhydrazone was trilithiated with excess lithium diisopropylamide, and the resulting trianion-type intermediate was condensed with a variety of aromatic esters followed by acid cyclization to 2-(1-phenyl-5-phenyl or 5-substituted phenyl-1H-pyrazol-3-yl)phenols.
  • Digital Object Identifier (doi)

    Author List

  • Rampey ME; Hurst DR; Sood A; Studer-Martinez SL; Beam CF
  • Start Page

  • 495
  • End Page

  • 506
  • Volume

  • 29
  • Issue

  • 3