Identification of channel-forming activity in the cell wall of Corynebacterium glutamicum

Academic Article


  • The cell wall of the gram-positive Corynebacterium glutamicum was prepared. It contained an ion-permeable channel with a single-channel conductance of about 6 nS in 1 M KCl. The mobility sequence of the ions in the channel is similar to that in the aqueous phase, suggesting that it is a water-filled channel wide enough to allow unhindered diffusion of ions. The results indicate that we have identified the hydrophilic pathway through the mycolic acid layer of C. glutamicum.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Niederweis M; Maier E; Lichtinger T; Benz R; Kramer R
  • Start Page

  • 5716
  • End Page

  • 5718
  • Volume

  • 177
  • Issue

  • 19