Gastrointestinal stromal tumors, version 2.2014.

Academic Article


  • Gastrointestinal stromal tumors (GIST) are the most common soft tissue sarcoma of the gastrointestinal tract, resulting most commonly from KIT or platelet-derived growth factor receptor α (PDGFRα)-activating mutations. These NCCN Guideline Insights highlight the important updates to the NCCN Guidelines for Soft Tissue Sarcoma specific to the management of patients with GIST experiencing disease progression while on imatinib and/or sunitinib.
  • Keywords

  • Benzamides, Gastrointestinal Stromal Tumors, Humans, Imatinib Mesylate, Indoles, Mutation, Piperazines, Proto-Oncogene Proteins c-kit, Pyrimidines, Pyrroles, Receptor, Platelet-Derived Growth Factor alpha, Sunitinib
  • Digital Object Identifier (doi)

    Author List

  • von Mehren M; Randall RL; Benjamin RS; Boles S; Bui MM; Casper ES; Conrad EU; DeLaney TF; Ganjoo KN; George S
  • Start Page

  • 853
  • End Page

  • 862
  • Volume

  • 12
  • Issue

  • 6