Severe hemolytic disease of the newborn from anti-e

Academic Article


  • Maternal antibody-mediated fetal red blood cell destruction secondary to non-D Rhesus (Rh) antibodies is a significant cause of hemolytic disease of the newborn (HDN). Here, we report a rare case of severe HDN associated with maternal antibody to Rh e. In addition to severe anemia, the infant developed thrombocytopenia, conjugated hyperbilirubinemia and cholelithiasis. Resolution of the infant's cholelithiasis occurred following treatment with ursodeoxycholic acid.
  • Authors

    Published In

    Digital Object Identifier (doi)

    Author List

  • McAdams RM; Dotzler SA; Winter LW; Kerecman JD
  • Start Page

  • 230
  • End Page

  • 232
  • Volume

  • 28
  • Issue

  • 3