Reaction to a surgical implant foreign body masquerading as recurrent uterine sarcoma

Academic Article


  • Background: Multiple products to prevent adhesions or lessen the risk of soft tissue attachments are commercially available. The long-term nature of these products is unknown, and they may cause foreign body reactions masquerading as recurrent disease in patients with cancer. Case: A perimenopausal female underwent a hysterectomy and placement of a surgical implant, polylactic acid. Final pathology revealed stage IA low-grade endometrial stromal sarcoma. Areas suspicious for recurrence were noted on radiographic imaging 1 year later, resulting in exploratory surgery. The suspicious areas were found to be foreign body reactions. Mass spectrometry identified the main component of the reactions as polylactic acid. Conclusion: Adhesion barriers and other surgical implants may not always be completely metabolized and should be used with caution in patients with cancer. © 2011 by The American College of Obstetricians and Gynecologists. Published by Lippincott Williams & Wilkins.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Shaltz AT; Leath CA; Wiedenhoefer JF; Sundborg MJ
  • Start Page

  • 450
  • End Page

  • 452
  • Volume

  • 117
  • Issue

  • 2 PART 2