Structure of Plasmodium falciparum ADP-ribosylation factor 1

Academic Article


  • Vesicular trafficking may play a crucial role in the pathogenesis and survival of the malaria parasite. ADP-ribosylation factors (ARFs) are among the major components of vesicular trafficking pathways in eukaryotes. The crystal structure of ARF1 GTPase from Plasmodium falciparum has been determined in the GDP-bound conformation at 2.5 Å resolution and is compared with the structures of mammalian ARF1s. © 2010 International Union of Crystallography All rights reserved.
  • Digital Object Identifier (doi)

    Pubmed Id

  • 9383850
  • Author List

  • Cook WJ; Smith CD; Senkovich O; Holder AA; Chattopadhyay D
  • Start Page

  • 1426
  • End Page

  • 1431
  • Volume

  • 66
  • Issue

  • 11