Gadopentetate-dimeglumine-enhanced MR imaging of gliomatosis cerebri: Appearance mimicking leptomeningeal tumor dissemination

Academic Article


  • The term gliomatosis cerebri was first used by Nevin in 1938 [1] and represents a neoplastic process of glial origin characterized by its diffuse pattern of infiltration along anatomic pathways [1, 2]. Radiologic methods of detecting gliomatosis cerebi have relied heavily on CT [3-6]. Recently, the efficacy of MR imaging in detecting this disease has been described [7, 8]. We report a case of histologically documented gliomatosis cerebri that on gadopentetate-dimeglumine-enhanced MR images exhibited an enhancement pattern that mimicked one that has been seen in children with leptomeningeal spread of primary intracranial neoplasms [9, 10]. In our case, examination of the CNS at autopsy demonstrated an absence of leptomeningeal tumor but provided a morphologic explanation for the appearance of the contrast-enhanced MR examination.
  • Authors

    Published In

    Pubmed Id

  • 6641026
  • Author List

  • Rippe DJ; Boyko OB; Fuller GN; Friedman HS; Oakes WJ; Schold SC
  • Start Page

  • 800
  • End Page

  • 801
  • Volume

  • 11
  • Issue

  • 4