Simulated pulmonary nodules: Detection with dual-energy digital versus conventional radiography

Academic Article


  • Performance of a prototype dual-energy digital chest radiography unit in detecting calcified and noncalcified simulated pulmonary nodules was compared with that of a highly optimized, conventional system. Nodules ranging in size (0.5, 1.0, and 1.6 cm), in number (five to 11), and in calcium content (0-25 mg) were superimposed over the lungs of a frozen, unembalmed, human chest phantom. For each technique, six observers examined 50 posteroanterior projections with different randomized nodule locations. Detection consisted of locating and assigning a level of confidence to each perceived nodular opacity. The resulting plots of the true-positive fraction versus the mean number of false-positive calls per projection indicate that for both calcified and noncalcified nodules, the digital unit performed significantly better (P < .01).
  • Published In

  • Radiology  Journal
  • Digital Object Identifier (doi)

    Author List

  • Niklason LT; Hickey NM; Chakraborty DP; Sabbagh EA; Yester MV; Fraser RG; Barnes GT
  • Start Page

  • 589
  • End Page

  • 593
  • Volume

  • 160
  • Issue

  • 3