Hemangioblastoma of the Spinal Cord: Review and Report of Five Cases

Academic Article


  • Eighty-five cases of hemangioblastoma of the spinal cord are reviewed, including five new ones. While current views of the incidence, histology, and cytogenesis are presented, the main purpose of this article is to call attention to the identifying clinical and radiological characteristics of these spinal tumors. Median age at onset of symptoms was 30 years. The ratio of men to women was 1.1:1. Presenting symptoms were usually radicular pain or posterior column sensory loss or both. The lesions were most often single (79%), intramedullary (60%), and located in the cervical or thoracic spinal cord. There was associated syringomyelia in 67% of intramedullary cases and meningeal varicosities in 48% of all cases. Lindau disease and hemangioblastomas in other central nervous system locations were present in 33% of cases. The characteristic roentgenographic picture is a densely vascular tumor in association with a larger avascular syrinx and meningeal varicosities. Surgery is the only definitive treatment. © 1976, American Medical Association. All rights reserved.
  • Published In

  • JAMA Neurology  Journal
  • Digital Object Identifier (doi)

    Author List

  • Browne TR; Adams RD; Roberson GH
  • Start Page

  • 435
  • End Page

  • 441
  • Volume

  • 33
  • Issue

  • 6