Mast cell cholangiopathy: Another cause of sclerosing cholangitis

Academic Article


  • A 75-year-old woman with known systemic mastocytosis presented with abdominal pain, ascites, and bile duct thickening on computed tomography and ultrasonography. A liver biopsy specimen showed infiltration with mast cells. Endoscopic retrograde cholangiography showed ductal changes compatible with those found in primary sclerosing cholangitis. Brush cytology of the intrahepatic bile ducts confirmed mast cell infiltration. Systemic mastocytosis can infiltrate the biliary system, producing a cholangiopathy radiographically similar to primary sclerosing cholangitis. © 1995.
  • Authors

    Published In

  • Gastroenterology  Journal
  • Digital Object Identifier (doi)

    Author List

  • Baron TH; Koehler RE; Rodgers WH; Fallon MB; Ferguson SM
  • Start Page

  • 1677
  • End Page

  • 1681
  • Volume

  • 109
  • Issue

  • 5