Surgical and anesthetic management of a mediastinal fatty tumor: Lipoblastoma

Academic Article


  • Lipoblastoma is a rare fatty tumor that is diagnosed almost exclusively in children. Presentation often consists of respiratory symptoms; chest computed tomography shows a hypodense, low, attenuated mediastinal mass. Surgical approach and anesthetic management are dependent on the location of the tumor and the degree of airway compression; in most cases, a thoracotomy is performed, although a sternotomy is used in selected cases. Final diagnosis can be confirmed using molecular genetic analysis; a genetic hallmark of lipoblastoma is the rearrangement of chromosomal region 8q12 and the PLAG1 gene. Tumor recurrence is rare when a complete resection is performed.
  • Published In

    Digital Object Identifier (doi)

    Pubmed Id

  • 17435658
  • Author List

  • Al-Mubarak G; Bryant AS; Crawford JH; Dukes CM; Kelly DR; Young DW; Cleveland DC
  • Start Page

  • e97
  • End Page

  • e98
  • Volume

  • 100
  • Issue

  • 5