Primary Vulvar Adenocarcinoma of Cloacogenic Origin

Academic Article


  • A 43-year-old woman who had a vulvar mass associated with mild discomfort was found to have a rare primary vulvar adenocarcinoma of probable cloacal origin. The tumor was contiguous with the surface epithelium of the vulva and was a well to moderately differentiated adenocarcinoma of colonic type. Stains of the neoplastic cells were positive for both acid and neutral mucin, and periodic acid-Schiff (PAS) was positive after diastase reaction. The neoplastic cells were strongly positive for carcinoembryonic antigen, broad spectrum cytokeratin, and p-53 antigen. Clinical evaluation failed to show any primary tumor in colon, lung, or breast. The patient was disease free 18 months after operation.
  • Authors

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    Digital Object Identifier (doi)

    Author List

  • Nasir S; Zaidi H; Conner MG
  • Start Page

  • 744
  • End Page

  • 746
  • Volume

  • 94
  • Issue

  • 7