The rostral and caudal ventrolateral medulla in young spontaneously hypertensive rats

Academic Article


  • This study was designed to compare the cardiovascular influences of the rostral ventrolateral medulla (RVLM) and the caudal ventrolateral medulla (CVLM) in young (5-6 weeks) spontaneously hypertensive (SH) and normotensive Wistar-Kyoto (WKY) rats. SH and WKY groups had similar pressor and depressor responses to microinjection of l-glutamate into the RVLM and the CVLM, respectively. In addition the results of this study indicate a reduced tonic sympathoinhibitory function of the CVLM in young SH rats, which may contribute to the development of hypertension in the spontaneously hypertensive rat. © 1990.
  • Published In

  • Brain Research  Journal
  • Digital Object Identifier (doi)

    Author List

  • Smith JK; Barron KW
  • Start Page

  • 153
  • End Page

  • 158
  • Volume

  • 506
  • Issue

  • 1