Novel pyridopyrazine and pyrimidothiazine derivatives as FtsZ inhibitors

Academic Article

Abstract

  • A series of pyridopyrazine and pyrimidothiazine derivatives have been synthesized and their activity against FtsZ from Mycobacterium tuberculosis (Mtb) and in vitro antibacterial activity against Mtb H 37Ra and Mtb H 37Rv are reported. Certain analogs described herein showed moderate to good inhibitory activity. © 2011 Elsevier Ltd. All rights reserved.

    • Authors

    Published In

    Digital Object Identifier (doi)

    Author List

  • Mathew B; Srivastava S; Ross LJ; Suling WJ; White EL; Woolhiser LK; Lenaerts AJ; Reynolds RC

    • Start Page

  • 7120

    • End Page

  • 7128

    • Volume

  • 19

    • Issue

  • 23